Journal of Inorganic Materials ›› 2026, Vol. 41 ›› Issue (4): 432-444.DOI: 10.15541/jim20250144
• REVIEW • Previous Articles Next Articles
LI Xuan1,2(
), YE Kuicai1, FENG Jiayin1, QIU Jiajun3, QIAN Wenhao1(), XING Min1()
Received:2025-04-07
Revised:2025-06-05
Published:2026-04-20
Online:2025-06-27
Contact:
XING Min, associate professor. E-mail: xingmin0821@126.com;About author:LI Xuan (2000-), female, Master candidate. E-mail: 2233092@mail.dhu.edu.cn
Supported by:CLC Number:
LI Xuan, YE Kuicai, FENG Jiayin, QIU Jiajun, QIAN Wenhao, XING Min. Surface Modification of Titanium-based Dental Implants for Soft Tissue Sealing: A Review[J]. Journal of Inorganic Materials, 2026, 41(4): 432-444.
Fig. 1 Oral microenvironment and soft tissue around titanium-based dental implants along with various surface modification techniques[7]
Fig. 2 Schematic diagram of peri-implant tissue structure[6]
Fig. 3 Soft tissue sealing and antibacterial effects promoted by layer-by-layer self-assembly method[27-28,30] (a) Schemetic diagram of TA-Ce-Mino coating design and SEM images showing topography of the coating[27]; (b) Hemidesmosome detected by TEM[28]; (c) Immunohistochemistry staining results of expression of the hemidesmosome related protein laminin 5α3[28]; (d) Antibacterial efficacy of Ti-PEMs samples against P. gingivalis[30]
Fig. 4 Schematic diagram of titanium-based coating prepared by electrochemical deposition and its effect on promoting cell migration[34] (a) Electrochemical deposition model for modification of Col-Ι on Ti[34]; (b1-b3) SEM images of L929 fibroblast cell reseeding on (b1) untreated Ti, (b2) TiO2 porous surface and (b3) coated Ti/Col-Ι (scale bar: 10 and 2 μm, respectively)[34]
Fig. 5 Schematic diagram of titanium-based coating prepared by plasma spraying[38]
Fig. 6 Soft tissue sealing and antibacterial effects promoted by anodic oxidation method [75-76,78 -79] (a) Soft tissue sealing efficacy promoted by TNT-30, TNT-40 and TNT-50 (scale bar: 100 μm)[75]; (b) Soft tissue sealing efficacy promoted by Fe-NC@TNT[76]; (c) Thirty-day cumulative average quantity of doxycycline released under pH 5.4, 6.4 and 7.4[78]; (d) Antibacterial activity of TNTs-Van@ZnO-FA under different pH against S. aureus[79]
Fig. 7 Titanium-based coating prepared by micro-arc oxidation and its effect on promoting soft tissue sealing[82-84] (a) Schematic illustration of titanium-based coating fabrication via micro-arc oxidation and characteristic surface morphology[82-83]; (b) Schematic diagram of CCN2@MSNs-Ti prepared by micro-arc oxidation[84]; (c) Effects of S-Ti, MAO-Ti, and CCN2@MSNs-Ti on HDFs migration (scale bar: 50 (left) and 10 (right) μm, respectively)[84]; (d) Fluorescence staining of HGFs for incubation on Ti and MAO treated surfaces without UV treatment (UV−) and with UV treatment (UV+)[82]
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