Advances in Regulation of Damaged Skin Regeneration by Two-dimensional Inorganic Materials

doi:10.15541/jim20240508

Abstract

Abstract: Two-dimensional（2D）inorganic materials , as a class of inorganic ultrathin nanosheets with single or several atomic layers, exhibit high specific surface area, electrical conductivity and/or photothermal conversion efficiency. These unique physicochemical properties confer procoagulant, antibacterial, anti-inflammatory, and antioxidant biological effects. In recent years, in view of degradation and metabolism issues, these materials have been explored for the modulation of diseased skin tissues, such as full-thickness wounds, burns and diabetic wounds, demonstrating remarkable effects in accelerating wound healing, alleviating infections and improving the inflammatory microenvironment. This manuscript focuses on the unique structure and biological effects of 2D inorganic materials, systematically describes their applications in wound healing and related mechanisms, and looks forward to current challenges and prospects of the 2D inorganic materials in the field of skin repair.

Key words: inorganic material, two-dimensional nanomaterial, skin repair, microenvironmental regulation, review

CLC Number:

XIAO Xiaolin, WANG Yuxiang, GU Peiyang, ZHU Zhenrong, SUN Yong. Advances in Regulation of Damaged Skin Regeneration by Two-dimensional Inorganic Materials[J]. Journal of Inorganic Materials, DOI: 10.15541/jim20240508.

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