Synthesis and Characterization of Bionic Nano-silicon-substituted Hydroxyapatite

doi:10.3724/SP.J.1077.2013.12292

Abstract

Abstract:

To explore the synthesis condition of the bionic nano-silicon-substituted hydroxyapatite and the impact of the silicon content on its crystallization properties, hydroxyapatite of different silicon content were synthesized from Ca(NO₃)₂, (NH₄)₂HPO₄ and Si(OCH₂CH₃)₄(TEOS) via an aqueous precipitation reaction. Fourier transform infrared spectroscopy (FTIR), X-ray fluorescence spectrum (XRF), X-ray diffraction (XRD) and transmission electron microscopy (TEM) were used for hydroxyapatite characterization. The results show that relative low temperature (40℃) is conducive to obtain pure bionic nano-silicon-substituted hydroxyapatite. Under this condition, SiO₄^4- enters the lattice of hydroxyapatite and replaces part of PO₄^3-. The more the content of silicon is, the lower the crystallinity is, the smaller the grain size is and the higher the lattice parameters a and c are.

Key words: silicon, hydroxyapatite, aqueous precipitation reaction, bionoid

CLC Number:

TQ174

ZHAI Qian-Qian, ZHAO Shi-Gui, WANG Xiao-Hai, LI Xiu-Zhi, LI Wen-Jie, ZHENG Ya-Sen. Synthesis and Characterization of Bionic Nano-silicon-substituted Hydroxyapatite[J]. Journal of Inorganic Materials, 2013, 28(1): 58-62.

Figures/Tables 11

References 11

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Samples	Ca(NO₃)₂ /mol	(NH₄)₂HPO₄ /mol	TEOS /mol	Expected w(Si)/%	Calculated chemical formula of Si-HA
HA	0.025	0.01500	0.00000	0	Ca₁₀(PO₄)₆(OH)₂
2%Si-HA	0.025	0.01470	0.00030	0.335	Ca₁₀(PO₄)_5.88(SiO₄)_0.12(OH)_1.88
7%Si-HA	0.025	0.01395	0.00105	1.181	Ca₁₀(PO₄)_5.58(SiO₄)_0.42(OH)_1.58
12%Si-HA	0.025	0.01320	0.00180	2.037	Ca₁₀(PO₄)_5.28(SiO₄)_0.72(OH)_1.28
17%Si-HA	0.025	0.01245	0.00255	2.903	Ca₁₀(PO₄)_4.98(SiO₄)_1.02(OH)_0.98

Samples	Ca(NO₃)₂ /mol	(NH₄)₂HPO₄ /mol	TEOS /mol	Expected w(Si)/%	Calculated chemical formula of Si-HA
HA	0.025	0.01500	0.00000	0	Ca₁₀(PO₄)₆(OH)₂
2%Si-HA	0.025	0.01470	0.00030	0.335	Ca₁₀(PO₄)_5.88(SiO₄)_0.12(OH)_1.88
7%Si-HA	0.025	0.01395	0.00105	1.181	Ca₁₀(PO₄)_5.58(SiO₄)_0.42(OH)_1.58
12%Si-HA	0.025	0.01320	0.00180	2.037	Ca₁₀(PO₄)_5.28(SiO₄)_0.72(OH)_1.28
17%Si-HA	0.025	0.01245	0.00255	2.903	Ca₁₀(PO₄)_4.98(SiO₄)_1.02(OH)_0.98

Samples	Expected w(Si)/%	Found w(Si)/%	Expected w(Ca)/%	Found w(Ca)/%
HA	0	0	39.84	36.70
2%Si-HA	0.335	0.22	39.90	36.52
7%Si-HA	1.181	0.83	40.18	36.07
12%Si-HA	2.037	1.75	40.42	36.16
17%Si-HA	2.903	2.30	40.67	34.24

Samples	Expected w(Si)/%	Found w(Si)/%	Expected w(Ca)/%	Found w(Ca)/%
HA	0	0	39.84	36.70
2%Si-HA	0.335	0.22	39.90	36.52
7%Si-HA	1.181	0.83	40.18	36.07
12%Si-HA	2.037	1.75	40.42	36.16
17%Si-HA	2.903	2.30	40.67	34.24

Samples	Grain size/nm
Samples	c-axis	Average
HA	27	26.6
2%Si-HA	30.5	23.7
7%Si-HA	21.6	21.1
12%Si-HA	20.1	16.1
17%Si-HA	18.9	13