硅酸盐生物陶瓷/玻璃促创面修复的研究进展：作用、机制和应用方式

doi:10.15541/jim20250014

摘要/Abstract

摘要： 大面积皮肤创伤是全球公共卫生最具挑战性的问题之一,其修复与治疗给医疗保健系统造成了巨大的经济负担,亟需开发能够促进创面皮肤组织再生的高效伤口敷料。近年来,硅酸盐生物陶瓷/玻璃因具备促进血管再生、刺激细胞胶原蛋白沉积以及抗感染等多重优势,在创面修复领域得到了广泛的关注与应用。本文简要概述了硅酸盐生物陶瓷/玻璃在皮肤再生过程中的作用机制,介绍了硅酸盐生物陶瓷/玻璃材料和一些新技术的结合方法及其在创面修复领域的相关应用,最后总结了硅酸盐生物陶瓷/玻璃的优势与局限性,为硅酸盐生物陶瓷/玻璃材料在创面修复领域的临床应用提供参考。

关键词: 硅酸盐, 生物陶瓷/玻璃, 活性离子, 创面修复, 综述

Abstract: Extensive skin trauma represents one of the most challenging issues in global public health, and its repair and treatment impose a huge economic burden on healthcare systems. Therefore, there is an urgent need to develop an efficient wound dressing that can promote skin regeneration at the wound site. In recent years, silicate bioceramics/bioglass have received widespread attention and application in the field of wound healing due to their multiple advantages, including promoting angiogenesis, stimulating collagen deposition, and anti-infection properties. This paper provides a concise overview of the mechanisms through which silicate-based bioceramics and bioactive glass contribute to skin regeneration, analyzes their integration with emerging technologies and their applications in wound healing, and summarizes advantages and limitations of these materials. This review aims to inform and guide the future clinical application of silicate-based bioceramics and bioactive glass in wound healing.

Key words: silicate, bioceramic/bioglass, active ion, wound healing, review

中图分类号:

TQ171

王宇彤, 常江, 徐合, 吴成铁. 硅酸盐生物陶瓷/玻璃促创面修复的研究进展：作用、机制和应用方式[J]. 无机材料学报, DOI: 10.15541/jim20250014.

WANG Yutong, CHANG Jiang, XU He, WU Chengtie. Advances in Silicate Bioceramic/Glass for Wound Healing: Effects, Mechanisms and Application Ways[J]. Journal of Inorganic Materials, DOI: 10.15541/jim20250014.

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