无机生物材料用于毛囊和毛发再生的研究

doi:10.15541/jim20250002

摘要/Abstract

摘要： 由毛囊退化和缺失导致的脱发会严重影响人们的生活质量和心理健康,目前的临床治疗手段存在较大局限性。因此,毛囊和毛发再生是皮肤组织工程所面临的关键挑战之一。近年来,多种无机材料,尤其是生物陶瓷,被证实能够通过释放生物活性离子来调控细胞活动,具有促进组织修复和毛囊重建的积极作用。本综述首先介绍了皮肤组织和毛囊结构,之后列举了可促进毛囊再生的生物陶瓷种类及其相关重要进展。进而讨论了无机材料在毛囊再生中的不同应用形式。最后对生物陶瓷用于毛囊和毛发再生的未来发展方向作了总结与展望。本文旨在发掘生物陶瓷在毛发再生中的应用潜力,为毛囊损伤和脱发疾病的治疗提供新的参考策略。

关键词: 生物陶瓷, 毛囊, 毛发再生, 皮肤组织工程, 综述

Abstract: Hair loss caused by hair follicle degeneration can seriously affect individuals' quality of life and mental health. However, the clinical treatment methods for hair loss have several limitations. Hair follicle regeneration has emerged as a significant challenge in the field of skin tissue engineering. In recent years, various inorganic materials, particularly bioceramics, have been identified as capable of regulating cell activities by releasing bioactive ions, which positively influences skin tissue repair and hair follicle reconstruction. Herein, in this review, structure of the skin tissue and the hair follicle are introduced firstly, then the main types of bioceramics that can promote hair follicle regeneration are listed, followed by the related representative studies. Next, the different application forms of inorganic materials in hair follicle regeneration are discussed. Finally, the development direction of bioceramics for hair regeneration is summarized and prospected. This review highlights the potential of bioceramics in promoting hair regrowth, offering new strategies for treating hair follicle damage and hair loss disorders.

Key words: bioceramic, hair follicle, hair regrowth, skin tissue engineering, review

中图分类号:

TQ174

马景阁, 吴成铁. 无机生物材料用于毛囊和毛发再生的研究[J]. 无机材料学报, DOI: 10.15541/jim20250002.

MA Jingge, WU Chengtie. Potential Application of Bioceramics in Promoting Hair Follicle Regeneration and Hair Growth[J]. Journal of Inorganic Materials, DOI: 10.15541/jim20250002.

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