Journal of Inorganic Materials ›› 2023, Vol. 38 ›› Issue (1): 43-54.DOI: 10.15541/jim20220578
Special Issue: 【生物材料】抗菌与肿瘤治疗(202506)
• Topical Section: Anti-epidemic Biomaterials (Contributing Editor: YANG Yong) • Previous Articles Next Articles
WU Xuetong1,2(), ZHANG Ruofei2, YAN Xiyun2, FAN Kelong2(
)
Received:
2022-09-29
Revised:
2022-11-09
Published:
2023-01-20
Online:
2022-12-09
Contact:
FAN Kelong, professor. E-mail: fankelong@ibp.ac.cnAbout author:
WU Xuetong (2000-), female, PhD candidate. E-mail: wuxuetong21@mails.ucas.ac.cn
Supported by:
CLC Number:
WU Xuetong, ZHANG Ruofei, YAN Xiyun, FAN Kelong. Nanozyme: a New Approach for Anti-microbial Infections[J]. Journal of Inorganic Materials, 2023, 38(1): 43-54.
Fig. 2 Antibacterial killing effect of a nanozyme, Q-MOFCe0.5[32] (a, b) Plate count results of the antibacterial effects of Q-MOFCe0.5 on E. coli (a) and S. aureus (b); (c, d) Statistical results of the corresponding bacterial viability rates of E. coli (c) and S. aureus (d); (e) The live (SYTO-9, green)/dead (PI, red) staining results of E. coli and S. aureus; (f) Scanning electron microscope (SEM) results of bacterial samples treated by nanozymes Colorful figures are available on website
Fig. 3 Characterization and ROS generation ability of a nanozyme, Ag-TiO2 SAN[34] (a, b) Transmission electron microscope (TEM) images of Ag-TiO2 SAN co-localized with lysosomes of mouse (RAM 264.7) and human (THP-1) macrophages; (c, d) Ag-TiO2 SAN enhanced ROS generation. THP-1: a kind of human monocytic leukemia cell Colorful figures are available on website
Fig. 4 Characterization, Ag+ release, and ROS generation ability of Ag/BMO NPs through photodynamic combination therapy[47] (a) SEM image of Ag/BMO NPs; (b) Percentage release of Ag+ at pH 7.35 and pH 6.75 showing photo-enhanced ROS generation ability of Ag/BMO; (c) 1O2 detection result by probe of single oxygen sensor green; (d) ESR spectra of 1O2; (e) ·OH detection result by MB indicator; (f) ESR spectra of ·OH. L: 1064 nm laser (1 W·cm-2, 10 min) Colorful figures are available on website
Fig. 5 In vitro antimicrobial performance of Fe3O4-GOx based on cascaded reaction[50] (a) 2',7'-Dichlorofluorescein staining images of E. coli and MRSA; (b) Growth curves of MRSA; (c) Representative SEM and live/dead staining images of MRSA; (d) Crystal violet staining image and its absorbance for integrated MRSA biofilm Colorful figures are available on website
Fig. 6 S-Ab can be used as bio-orthogonal catalyst to complete shape-based selective recognition of bacteria and catalyze precursors into active antibacterial molecule[56] Colorful figure is available on website
Mechanism | Nanozyme | Catalytic activity | Mechanism | Pathogens | Ref. |
---|---|---|---|---|---|
Generation ROS | Cu-MOF | OXD | ROS | E. coli; S. aureus | [ |
Cu-CD | POD | ROS | E. coli; S. aureus | [ | |
Chitosan grafted Fe-doped-carbon dots (CS@Fe/CDs) | POD | ROS | P. aeruginosa; S. aureus. | [ | |
Ag-TiO2 SAN | POD | ROS | SARS-CoV-2 | [ | |
Fmoc-diphenylalanine hydrogel-eEncapsulated Pt | OXD; POD | ROS | E. coli; S. aureus | [ | |
CFO@BFO nanozyme-eel | CAT | ROS | E. coli; MRSA | [ | |
Cu2O@CuO; Cu@Cu2S nanodot | OXD; POD | ROS | E. coli; S. aureus | [ | |
FeCo@PDA NPs | POD | ROS | E. coli; S. aureus | [ | |
Fe3O4@SiO2@dendritic mesoporous silica@small-Fe3O4 nanoparticles | POD | ROS | E. coli | [ | |
Mesoporous vanadium oxide nanospheres | POD | ROS | E. coli; S. aureus | [ | |
Au3+-UiO-67 NMOFs | OXD; POD | ROS | E. coli; S. aureus | [ | |
CS@Fe3O4 | POD; SOD; CAT | ROS | A. baumannii | [ | |
N/Cl-CDs + Ag NPs | OXD | ROS | E. coli; S. aureus; MRSA | [ | |
Cu-N-C | OXD; POD | ROS | E. coli; S. aureus; B. cereus; C. albicans; MRSA | [ | |
PEGMA-co-GMA-co-AAm-HBPL-MnO2 hydrogel | CAT; POD | ROS | P. aeruginosa; S. aureus; E. coli | [ | |
GOx-MOF hydrogel | GOx; POD | ROS | E. coli; S. aureus | [ | |
Taurine-Cu-3(PO4)(2) hybrid nanoflower | POD | ROS | E. coli; S. aureus; B. cereus; C.albicans | [ | |
FePO4-HG | POD; SOD; CAT | ROS | E. coli; S. aureus | [ | |
Combination therapy | Au/MoO3-x | POD | Photothermal; ROS(O2•-) | MRSA | [ |
Cu-MOFN nanosheet | POD | Hot electron transferred ROS | S. aureus | [ | |
CuSeNPs@MPBA | POD | Photothermal; ROS | E. coli; S. aureus | [ | |
Hollow mesoporous Prussian blue nanoparticles (HMPBNPs) | POD | ROS; Photothermal | E. coli; S. aureus | [ | |
Bacitracin-functionalized dextran-MoSe2(AMP/dex-MoSe2 NSs) | POD | Photothermal; ROS | E. coli | [ | |
Mechanism | Nanozyme | Catalytic activity | Mechanism | Pathogens | Ref. |
Combination therapy | Ag/Bi2MoO6 | POD | Photodynamic; ROS | S. aureus | [ |
CuxO-PDA | POD | Photothermal; ROS | E. coli; S. aureus | [ | |
Histidine-containing carbon nanodots | OXD | Photodynamic; ROS | E. coli | [ | |
VOx-artificial enzyme | OXD, POD | Electron enhanced ROS | S. aureus | [ | |
EM@MoS2 | POD | Photothermal; ROS | S. aureus | [ | |
LS-CuS@PVA | POD | Photothermal; Photodynamic; ROS | E. coli; S. aureus | [ | |
D-A-conjugated COF | POD | Photothermal; Photodynamic; ROS | E. coli; S. aureus | [ | |
Cu3SnS4 NSs | POD | Photothermal; ROS | E. coli; S. aureus | [ | |
Mn3O4HNSs@ICG | OXD | Photothermal; Photodynamic; ROS | E. faecalis; E. coli; P. aeruginosa | [ | |
Au NCs@PCN MOF | POD | Photothermal; ROS | E. coli; S. aureus | [ | |
Ag (8.5%)@NiS2-x | POD | Photothermal; ROS | E. coli | [ | |
Cascaded reaction | Fe3O4-GOx | GOx; CAT; POD | ROS | E. coli; S. aureus | [ |
Fe2(MoO4)3@GOx | GOx; POD | ROS | E. coli; S. aureus | [ | |
ODex/gC/MoS2@Au@BSA Hydrogel | POD | ROS | E. coli; S. aureus | [ | |
CuO nanospheres | POD; CAT | ROS | E. coli; S. aureus | [ | |
MnFe2O4@MIL/Au&GOx(MMAG) | GOx; POD | ROS | E. coli; S. aureus | [ | |
Bio-orthogonal catalysis | Man-NZs(Au, FeTPP) | Bio-orthogonal catalysis | Salmonella; Lactobacillus sp. | [ | |
Man-NZ | Bio-orthogonal catalysis | E. coli; MSRA | [ | ||
E-Ab and S-Ab | Bio-orthogonal catalysis | E. coli; S. aureus | [ | ||
Others | CeO2@ZrO2 | Haloperoxidase | HBr- | E. coli; S. aureus | [ |
Table 1 Nanozymes for anti-microbial infections
Mechanism | Nanozyme | Catalytic activity | Mechanism | Pathogens | Ref. |
---|---|---|---|---|---|
Generation ROS | Cu-MOF | OXD | ROS | E. coli; S. aureus | [ |
Cu-CD | POD | ROS | E. coli; S. aureus | [ | |
Chitosan grafted Fe-doped-carbon dots (CS@Fe/CDs) | POD | ROS | P. aeruginosa; S. aureus. | [ | |
Ag-TiO2 SAN | POD | ROS | SARS-CoV-2 | [ | |
Fmoc-diphenylalanine hydrogel-eEncapsulated Pt | OXD; POD | ROS | E. coli; S. aureus | [ | |
CFO@BFO nanozyme-eel | CAT | ROS | E. coli; MRSA | [ | |
Cu2O@CuO; Cu@Cu2S nanodot | OXD; POD | ROS | E. coli; S. aureus | [ | |
FeCo@PDA NPs | POD | ROS | E. coli; S. aureus | [ | |
Fe3O4@SiO2@dendritic mesoporous silica@small-Fe3O4 nanoparticles | POD | ROS | E. coli | [ | |
Mesoporous vanadium oxide nanospheres | POD | ROS | E. coli; S. aureus | [ | |
Au3+-UiO-67 NMOFs | OXD; POD | ROS | E. coli; S. aureus | [ | |
CS@Fe3O4 | POD; SOD; CAT | ROS | A. baumannii | [ | |
N/Cl-CDs + Ag NPs | OXD | ROS | E. coli; S. aureus; MRSA | [ | |
Cu-N-C | OXD; POD | ROS | E. coli; S. aureus; B. cereus; C. albicans; MRSA | [ | |
PEGMA-co-GMA-co-AAm-HBPL-MnO2 hydrogel | CAT; POD | ROS | P. aeruginosa; S. aureus; E. coli | [ | |
GOx-MOF hydrogel | GOx; POD | ROS | E. coli; S. aureus | [ | |
Taurine-Cu-3(PO4)(2) hybrid nanoflower | POD | ROS | E. coli; S. aureus; B. cereus; C.albicans | [ | |
FePO4-HG | POD; SOD; CAT | ROS | E. coli; S. aureus | [ | |
Combination therapy | Au/MoO3-x | POD | Photothermal; ROS(O2•-) | MRSA | [ |
Cu-MOFN nanosheet | POD | Hot electron transferred ROS | S. aureus | [ | |
CuSeNPs@MPBA | POD | Photothermal; ROS | E. coli; S. aureus | [ | |
Hollow mesoporous Prussian blue nanoparticles (HMPBNPs) | POD | ROS; Photothermal | E. coli; S. aureus | [ | |
Bacitracin-functionalized dextran-MoSe2(AMP/dex-MoSe2 NSs) | POD | Photothermal; ROS | E. coli | [ | |
Mechanism | Nanozyme | Catalytic activity | Mechanism | Pathogens | Ref. |
Combination therapy | Ag/Bi2MoO6 | POD | Photodynamic; ROS | S. aureus | [ |
CuxO-PDA | POD | Photothermal; ROS | E. coli; S. aureus | [ | |
Histidine-containing carbon nanodots | OXD | Photodynamic; ROS | E. coli | [ | |
VOx-artificial enzyme | OXD, POD | Electron enhanced ROS | S. aureus | [ | |
EM@MoS2 | POD | Photothermal; ROS | S. aureus | [ | |
LS-CuS@PVA | POD | Photothermal; Photodynamic; ROS | E. coli; S. aureus | [ | |
D-A-conjugated COF | POD | Photothermal; Photodynamic; ROS | E. coli; S. aureus | [ | |
Cu3SnS4 NSs | POD | Photothermal; ROS | E. coli; S. aureus | [ | |
Mn3O4HNSs@ICG | OXD | Photothermal; Photodynamic; ROS | E. faecalis; E. coli; P. aeruginosa | [ | |
Au NCs@PCN MOF | POD | Photothermal; ROS | E. coli; S. aureus | [ | |
Ag (8.5%)@NiS2-x | POD | Photothermal; ROS | E. coli | [ | |
Cascaded reaction | Fe3O4-GOx | GOx; CAT; POD | ROS | E. coli; S. aureus | [ |
Fe2(MoO4)3@GOx | GOx; POD | ROS | E. coli; S. aureus | [ | |
ODex/gC/MoS2@Au@BSA Hydrogel | POD | ROS | E. coli; S. aureus | [ | |
CuO nanospheres | POD; CAT | ROS | E. coli; S. aureus | [ | |
MnFe2O4@MIL/Au&GOx(MMAG) | GOx; POD | ROS | E. coli; S. aureus | [ | |
Bio-orthogonal catalysis | Man-NZs(Au, FeTPP) | Bio-orthogonal catalysis | Salmonella; Lactobacillus sp. | [ | |
Man-NZ | Bio-orthogonal catalysis | E. coli; MSRA | [ | ||
E-Ab and S-Ab | Bio-orthogonal catalysis | E. coli; S. aureus | [ | ||
Others | CeO2@ZrO2 | Haloperoxidase | HBr- | E. coli; S. aureus | [ |
[1] |
WIERSINGA W J, RHODES A, CHENG A C, et al. Pathophysiology, transmission, diagnosis, and treatment of coronavirus disease 2019 (COVID-19): a review. JAMA-Journal of the American Medical Association, 2020, 324(8): 782.
DOI URL |
[2] |
GRIEF S N, LOZA J K. Guidelines for the evaluation and treatment of pneumonia. Primary Care, 2018, 45(3): 485.
DOI PMID |
[3] |
BLACK R E, MORRIS S S, BRYCE J. Where and why are 10 million children dying every year? Lancet, 2003. 361(9376): 2226,
DOI PMID |
[4] |
DENYS G A, RELICH R F. Antibiotic resistance in nosocomial respiratory infections. Clinics in Laboratory Medicine, 2014, 34(2): 257.
DOI PMID |
[5] |
YAP V, DATTA D, METERSKY M L. Is the present definition of health care-associated pneumonia the best way to define risk of infection with antibiotic-resistant pathogens? Infectious Disease Clinics of North America, 2013, 27(1): 1.
DOI PMID |
[6] |
BOUCHER H W, TALBOT G H, BRADLEY J S, et al. Bad bugs, no drugs: no eskape! An update from the infectious diseases society of America. Clinical Infectious Diseases, 2009, 48(1): 1.
DOI PMID |
[7] |
PITOUT J D D, LAUPLAND K B. Extended-spectrum beta-lactamase-producing enterobacteriaceae: an emerging public-health concern. Lancet Infectious Diseases, 2008, 8(3): 159.
DOI PMID |
[8] |
TONG S Y C, DAVIS J S, EICHENBERGER E, et al. Staphylococcus aureus infections: epidemiology, pathophysiology, clinical manifestations, and management. Clinical Microbiology Reviews, 2015, 28(3): 603.
DOI PMID |
[9] |
YANG R, XU J, XU L, et al. Cancer cell membrane-coated adjuvant nanoparticles with mannose modification for effective anticancer vaccination. ACS Nano, 2018, 12(6): 5121.
DOI PMID |
[10] |
ZHU G Z, LYNN G M, JACOBSON O, et al. Albumin/vaccine nanocomplexes that assemble in vivo for combination cancer immunotherapy. Nature Communications, 2017, 8: 1954.
DOI URL |
[11] |
LU J, LIONG M, LI Z, et al. Biocompatibility, biodistribution, and drug-delivery efficiency of mesoporous silica nanoparticles for cancer therapy in animals. Small, 2010, 6(16): 1794.
DOI PMID |
[12] |
TIAN Y, LI S, SONG J, et al. A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy. Biomaterials, 2014, 35(7): 2383.
DOI PMID |
[13] |
YANG Y, LI Z Y, YAMAGUCHI K, et al. Controlled fabrication of silver nanoneedles array for SERS and their application in rapid detection of narcotics. Nanoscale, 2012, 4(8): 2663.
DOI PMID |
[14] |
GAO L, ZHUANG J, NIE L, et al. Intrinsic peroxidase-like activity of ferromagnetic nanoparticles. Nature Nanotechnology, 2007, 2(9): 577.
DOI PMID |
[15] |
XU B, WANG H, WANG W, et al. A single-atom nanozyme for wound disinfection applications. Angewandte Chemie International Edition, 2019, 58(15): 4911.
DOI URL |
[16] |
ZHAO H Q, ZHANG R F, YAN X Y, et al. Superoxide dismutase nanozymes: an emerging star for anti-oxidation. Journal of Materials Chemistry B, 2021, 9(35): 6939.
DOI PMID |
[17] |
HU X, LI F Y, XIA F, et al. Biodegradation-mediated enzymatic activity-tunable molybdenum oxide nanourchins for tumor-specific cascade catalytic therapy. Journal of the American Chemical Society, 2020, 142(3): 1636.
DOI PMID |
[18] |
MENG X, LI D, CHEN L, et al. High-performance self-cascade pyrite nanozymes for apoptosis-ferroptosis synergistic tumor therapy. ACS Nano, 2021, 15(3): 5735.
DOI PMID |
[19] | JIANG B, YAN L, ZHANG J, et al. Biomineralization synthesis of the cobalt nanozyme in SP94-ferritin nanocages for prognostic diagnosis of hepatocellular carcinoma. ACS Applied Materials & Interfaces, 2019, 11(10): 9747. |
[20] |
JIANG D W, NI D L, ROSENKRANS Z T, et al. Nanozyme: new horizons for responsive biomedical applications. Chemical Society Reviews, 2019, 48(14): 3683.
DOI PMID |
[21] |
WANG Z, LI G, GAO Y, et al. Trienzyme-like iron phosphates-based (FePOs) nanozyme for enhanced anti-tumor efficiency with minimal side effects. Chemical Engineering Journal, 2021, 404: 125574.
DOI URL |
[22] | ZHANG Y A, LI Y N, ZHANG J L, et al. Nanocage-based capture-detection system for the clinical diagnosis of autoimmune disease. Small, 2021, 17(25): 2101655. |
[23] |
DUAN D, FAN K, ZHANG D, et al. Nanozyme-strip for rapid local diagnosis of ebola. Biosensors & Bioelectronics, 2015, 74: 134.
DOI URL |
[24] |
MENG X, ZOU S, LI D, et al. Nanozyme-strip for rapid and ultrasensitive nucleic acid detection of SARS-CoV-2. Biosensors & Bioelectronics, 2022, 217: 114739.
DOI URL |
[25] |
MAO Z, CHEN J, WANG Y, et al. Copper metal organic framework as natural oxidase mimic for effective killing of gram- negative and gram-positive bacteria. Nanoscale, 2022, 14(26): 9474.
DOI URL |
[26] | CAO M, CHANG Z, TAN J, et al. Superoxide radical-mediated self-synthesized Au/MoO(3-x) hybrids with enhanced peroxidase-like activity and photothermal effect for anti-MRSA therapy. ACS Applied Materials & Interfaces, 2022, 14(11): 13025. |
[27] | WANG Y, YAO J, CAO Z, et al. Peroxidase-mimetic copper-doped carbon-dots for oxidative stress-mediated broad-spectrum and efficient antibacterial activity. Chemistry-a European Journal, 2022, 28: e202104174. |
[28] |
FUENTES K M, ONNA D, RIOUAL T, et al. Copper upcycling by hierarchical porous silica spheres functionalized with branched polyethylenimine: antimicrobial and catalytic applications. Microporous and Mesoporous Materials, 2021, 327: 111391.
DOI URL |
[29] |
SINGH N, SAVANUR M A, SRIVASTAVA S, et al. A redox modulatory Mn3O4 nanozyme with multi-enzyme activity provides efficient cytoprotection to human cells in a Parkinson's disease model. Angewandte Chemie International Edition, 2017, 56(45): 14267.
DOI URL |
[30] |
MU X, WANG J, LI Y, et al. Redox trimetallic nanozyme with neutral environment preference for brain injury. ACS Nano, 2019, 13(2): 1870.
DOI PMID |
[31] |
AI Y, YOU J, GAO J, et al. Multi-shell nanocomposites based multienzyme mimetics for efficient intracellular antioxidation. Nano Research, 2021, 14(8): 2644.
DOI URL |
[32] |
HUANG L, SUN D W, PU H. Photosensitized peroxidase mimicry at the hierarchical 0D/2D heterojunction-like quasi metal-organic framework interface for boosting biocatalytic disinfection. Small, 2022, 18(20): 2200178.
DOI URL |
[33] |
PAN T, CHEN H, GAO X, et al. Engineering efficient artificial nanozyme based on chitosan grafted Fe-doped-carbon dots for bacteria biofilm eradication. Journal of Hazardous Materials, 2022, 435: 128996.
DOI URL |
[34] |
WANG D, ZHANG B, DING H, et al. TiO2 supported single Ag atoms nanozyme for elimination of SARS-COV2. Nano Today, 2021, 40: 101243.
DOI URL |
[35] |
NI Y, WANG J, WANG M, et al. COVID-19-inspired "artificial virus" to combat drug-resistant bacteria by membrane-intercalation- photothermal-photodynamic multistage effects. Chemical Engineering Journal, 2022, 446: 137322.
DOI URL |
[36] |
SARINA S, WACLAWIK E R, ZHU H. Photocatalysis on supported gold and silver nanoparticles under ultraviolet and visible light irradiation. Green Chemistry, 2013, 15(7): 1814.
DOI URL |
[37] |
MU M, WEN S, HU S, et al. Putting surface-enhanced Raman spectroscopy to work for nanozyme research: methods, materials and applications. Trac-Trends in Analytical Chemistry, 2022, 152: 116603.
DOI URL |
[38] |
LIAO X, XU Q, SUN H, et al. Plasmonic nanozymes: localized surface plasmonic resonance regulates reaction kinetics and antibacterial performance. Journal of Physical Chemistry Letters, 2022, 13(1): 312.
DOI PMID |
[39] | LI L, YANG J, WEI J, et al. SERS monitoring of photoinduced- enhanced oxidative stress amplifier on Au@carbon dots for tumor catalytic therapy. Light-Science & Applications, 2022, 11(1): 286. |
[40] |
WANG D, FANG Y, YU W, et al. Significant solar energy absorption of mxene Ti3C2Tx nanofluids via localized surface plasmon resonance. Solar Energy Materials and Solar Cells, 2021, 220: 110850.
DOI URL |
[41] |
ZANDI O, AGRAWAL A, SHEARER A B, et al. Impacts of surface depletion on the plasmonic properties of doped semiconductor nanocrystals. Nature Materials, 2018, 17(8): 710.
DOI PMID |
[42] |
GENG X, ZHANG D, ZHENG Z, et al. Integrated multifunctional device based on Bi2S3/Pd: localized heat channeling for efficient photothermic vaporization and real-time health monitoring. Nano Energy, 2021, 82: 105700.
DOI URL |
[43] |
CHEN X, WANG X, FANG Y, et al. Long-lasting chemiluminescence- based poct for portable and visual pathogenic detection and in situ inactivation. Analytical Chemistry, 2022, 94: 8382.
DOI URL |
[44] |
LI Y, ZHU Y, WANG C, et al. Mild hyperthermia induced by hollow mesoporous prussian blue nanoparticles in alliance with a low concentration of hydrogen peroxide shows powerful antibacterial effect. Molecular Pharmaceutics, 2022, 19(3): 819.
DOI URL |
[45] | LIN T, JIANG G, LIN D, et al. Bacitracin-functionalized dextran- mose 2 with peroxidase-like and near-infrared photothermal activities for low-temperature and synergetic antibacterial applications. ACS Applied Biomaterials, 2022, 5(5): 2347. |
[46] |
SONGCA S P, ADJEI Y. Applications of antimicrobial photodynamic therapy against bacterial biofilms. International Journal of Molecular Sciences, 2022, 23(6): 3209.
DOI URL |
[47] |
GAO C, ZHANG T, YANG N, et al. POD nanozyme optimized by charge separation engineering for light/pH activated bacteria catalytic/photodynamic therapy. Signal Transduction and Targeted Therapy, 2022, 7(1): 86.
DOI PMID |
[48] | HE S, FENG Y, SUN Q, et al. Charge-switchable CuxO nanozyme with peroxidase and near-infrared light enhanced photothermal activity for wound antibacterial application. ACS Applied Materials & Interfaces, 2022, 14(22): 25042. |
[49] |
LOUKANOV A, KURIBARA A, NIKOLOVA S, et al. Light-activated oxidize-mimicking nanozyme for inhibition of pathogenic escherichia coli. Microscopy Research and Technique, 2022, 85(5): 1949.
DOI PMID |
[50] |
DU X, JIA B, WANG W, et al. pH-switchable nanozyme cascade catalysis: a strategy for spatial-temporal modulation of pathological wound microenvironment to rescue stalled healing in diabetic ulcer. Journal of Nanobiotechnology, 2022, 20(1): 12.
DOI PMID |
[51] | ZHANG Y, LI D, XU Y, et al. Application of a cascaded nanozyme in infected wound recovery of diabetic mice. ACS Biomaterials Science & Engineering, 2022, 8(4): 1522. |
[52] |
FEDELI S, IM J, GOPALAKRISHNAN S, et al. Nanomaterial-based bioorthogonal nanozymes for biological applications. Chemical Society Reviews, 2021, 50(24): 13467.
DOI PMID |
[53] |
NGUYEN S S, PRESCHER J A. Developing bioorthogonal probes to span a spectrum of reactivities. Nature Reviews Chemistry, 2020, 4(9): 476.
DOI PMID |
[54] |
HARDIE J, MAKABENTA J M, GUPTA A, et al. Selective treatment of intracellular bacterial infections using host cell-targeted bioorthogonal nanozymes. Materials Horizons, 2022, 9(5): 1489.
DOI URL |
[55] |
GUPTA A, DAS R, MAKABENTA J M, et al. Erythrocyte-mediated delivery of bioorthogonal nanozymes for selective targeting of bacterial infections. Materials Horizons, 2021, 8(12): 3424.
DOI PMID |
[56] |
NIU J, WANG L, CUI T, et al. Antibody mimics as bio-orthogonal catalysts for highly selective bacterial recognition and antimicrobial therapy. ACS Nano, 2021, 15(10): 15841.
DOI PMID |
[57] | CHEN J, ZHANG S, CHEN X, et al. A self-assembled fmoc-diphenylalanine hydrogel-encapsulated Pt nanozyme as oxidase-and peroxidase-like breaking ph limitation for potential antimicrobial application. Chemistry-a European Journal, 2022, 28(26): e202104247. |
[58] |
DENG Q, ZHANG L, LIU X, et al. Magnetoelectrically ignited nanozyme-eel for combating bacterial biofilms. Chemical Communications, 2022, 58(55): 7634.
DOI URL |
[59] |
HE Y, YIN M, SUN J, et al. Excellent catalytic properties of luminescent Cu@Cu2S nanozymes and their antibacterial applications. Chemical Communications, 2022, 58(18): 2995.
DOI URL |
[60] |
KUANG F, CHEN Y, SHAN W, et al. Biomimetic FeCo@Pd a nanozyme platform with fenton catalytic activity as efficient antibacterial agent. Journal of Materials Chemistry B, 2022, 10(29): 5582.
DOI URL |
[61] |
HUANG Y, LIU D, GUO R, et al. Magnetic-controlled dandelion-like nanocatalytic swarm for targeted biofilm elimination. Nanoscale, 2022, 14(17): 6497.
DOI URL |
[62] |
LI P, FENG Y, CHENG D, et al. Self-template synthesis of mesoporous vanadium oxide nanospheres with intrinsic peroxidase-like activity and high antibacterial performance. Journal of Colloid and Interface Science, 2022, 625: 435.
DOI PMID |
[63] |
PAN M M, OUYANG Y, SONG Y L, et al. Au3+-functionalized UIO-67 metal-organic framework nanoparticles: O2-(center dot-) and center dot OH generating nanozymes and their antibacterial functions. Small, 2022, 18(23): 2200548.
DOI URL |
[64] |
WANG W, WU Z, SHI P, et al. Antibacterial effect of chitosan-modified Fe3O4 nanozymes on Acinetobacter baumannii. Journal of Microbiology and Biotechnology, 2022, 32(2): 263.
DOI URL |
[65] |
ZHU J, LI Q, LI X, et al. Simulated enzyme activity and efficient antibacterial activity of copper-doped single-atom nanozymes. Langmuir, 2022, 38(22): 6860.
DOI URL |
[66] |
ZHU J, LI X, WU X, et al. Nanocomposite of Ag nanoparticles and deep eutectic solvent-derived carbon dots with oxidase mimicking activity as synergistic bactericidal agent. Letters in Applied Microbiology, 2022, 74(5): 684.
DOI URL |
[67] |
TU C, LU H, ZHOU T, et al. Promoting the healing of infected diabetic wound by an anti-bacterial and nano-enzyme-containing hydrogel with inflammation-suppressing, ROS-scavenging, oxygen and nitric oxide-generating properties. Biomaterials, 2022, 286: 121597.
DOI URL |
[68] |
ZHANG S, DING F, LIU Y, et al. Glucose-responsive biomimetic nanoreactor in bacterial cellulose hydrogel for antibacterial and hemostatic therapies. Carbohydrate Polymers, 2022, 292: 119615.
DOI URL |
[69] |
YILMAZ S G, DEMIRBAS A, KARAAGAC Z, et al. Synthesis of taurine-Cu3(PO4)2 hybrid nanoflower and their peroxidase-mimic and antimicrobial properties. Journal of Biotechnology, 2022, 343: 96.
DOI URL |
[70] | LIAO Z Y, GAO W W, SHAO N N, et al. Iron phosphate nanozyme-hydrogel with multienzyme-like activity for efficient bacterial sterilization. ACS Applied Materials & Interfaces, 2022, 14(16): 18170. |
[71] |
LI L, CAO S, WU Z, et al. Modulating electron transfer in vanadium-based artificial enzymes for enhanced ROS-catalysis and disinfection. Advanced Materials, 2022, 34(17): 2108646.
DOI URL |
[72] |
SHI T, RUAN Z, WANG X, et al. Erythrocyte membrane- enveloped molybdenum disulfide nanodots for biofilm elimination on implants via toxin neutralization and immune modulation. Journal of Materials Chemistry B, 2022, 10(11): 1805.
DOI URL |
[73] | XIE Y, GAN C, LI Z, et al. Fabrication of a lignin-copper sulfide-incorporated PVA hydrogel with near-infrared-activated photothermal/photodynamic/peroxidase-like performance for combating bacteria and biofilms. ACS Biomaterials Science & Engineering, 2022, 8(2): 560. |
[74] | YANG G P, MENG X L, XIAO S J, et al. Construction of D-a-conjugated covalent organic frameworks with enhanced photodynamic, photothermal, and nanozymatic activities for efficient bacterial inhibition. ACS Applied Materials & Interfaces, 2022, 14(24): 28289. |
[75] |
YANG Y, WANG C, WANG N, et al. Photogenerated reactive oxygen species and hyperthermia by Cu3SnS4 nanoflakes for advanced photocatalytic and photothermal antibacterial therapy. Journal of Nanobiotechnology, 2022, 20(1): 195.
DOI URL |
[76] |
ZHANG X, MIN Y, ZHANG Q, et al. Functionalized Mn3O4 nanosheets with photothermal, photodynamic, and oxidase-like activities triggered by low-powered near-infrared light for synergetic combating multidrug-resistant bacterial infections. Advanced Healthcare Materials, 2022, 11(12): 2200121.
DOI URL |
[77] | ZHAO X, CHANG L, HU Y, et al. Preparation of photocatalytic and antibacterial MOF nanozyme used for infected diabetic wound healing. ACS Applied Materials & Interfaces, 2022. 14(16): 18194. |
[78] |
ZHANG Y, YANG D, GUO W, et al. A multifunctional hydrogel dressing with antibacterial properties for effective wound healing. Dalton Transactions, 2022, 51(17): 6817.
DOI URL |
[79] |
LI Y, FU R, DUAN Z, et al. Injectable hydrogel based on defect-rich multi-nanozymes for diabetic wound healing via an oxygen self-supplying cascade reaction. Small, 2022, 18(18): 2200165.
DOI URL |
[80] |
WANG P, PENG L, LIN J, et al. Enzyme hybrid virus-like hollow mesoporous CuO adhesive hydrogel spray through glucose-activated cascade reaction to efficiently promote diabetic wound healing. Chemical Engineering Journal, 2021, 415: 128901.
DOI URL |
[81] | ZHOU X, ZHANG S, LIU Y, et al. Antibacterial cascade catalytic glutathione-depleting MOF nanoreactors. ACS Applied Materials & Interfaces, 2022, 14(9): 11104. |
[82] |
LUO Q, LI Y, HUO X, et al. Stabilizing ultrasmall ceria-cluster nanozyme for antibacterial and antibiofouling applications. Small, 2022, 18(16): 2107401.
DOI URL |
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