Bismuth Sulfide Nanoclusters-loaded Silica-based Hybrid Micelles: Preparation and Photothermal Antibacterial Property

doi:10.15541/jim20240530

Abstract

Abstract: As a new type of photothermal compound, bismuth-based nanomaterials have advantages of low price, low toxicity, environmental friendliness and cheap raw materials, showing great application potential in biological photothermal therapy, but its photothermal conversion efficiency and antibacterial property are still low. In this paper, based on the confined gelation method reported by our previous literature, a silica-based hybrid micellar precursor with organosilica-stabilized micellar cores was prepared using Pluronic polymer F127 and 3-mercaptopropyl-trimethoxy- silane as raw materials, and a facile "confined reduction/sulfuration " method was further developed, that is, the abundant thiols groups in the organosilica framework of the micelle core were used as restricted adsorption site, sodium borohydride was used as reducing agent, and sodium sulfide was used as the vulcanizing agent to prepare ultra-small and amorphous bismuth sulfide clusters-supported silica-based hybrid micellar system. The results show that the functional hybrid micellar system has excellent photothermal performance, and its photothermal conversion efficiency is up to 86.9%, which may be attributed to monodisperse and stable loading of bismuth sulfide clusters with defective structure in the organosilica framework of hybrid micellar system, which enhances tlight absorption capacity of bismuth sulfide nanomaterials in the near-infrared wavelength range. The in vitro antimicrobial experiments showed that this bismuth-containing system exhibited excellent photothermal antibacterial properties under irradiation of 808 nm near-infrared laser and good biocompatibility.

Key words: silica, block copolymer, bismuth sulfide, photothermal property, antibacterial agent

CLC Number:

TQ174

ZHAO Lihua, WANG Yanshuai, YIN Xinwu, MAO Yeqiong, NIU Dechao. Bismuth Sulfide Nanoclusters-loaded Silica-based Hybrid Micelles: Preparation and Photothermal Antibacterial Property[J]. Journal of Inorganic Materials, DOI: 10.15541/jim20240530.

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