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无机材料学报

无机材料学报 ›› 2025, Vol. 40 ›› Issue (5): 449-456.DOI: 10.15541/jim20250006

所属专题： 【生物材料】抗菌与肿瘤治疗(202506)； 【生物材料】骨骼与齿类组织修复(202506)

• 学科评述 •    下一篇

无机非金属生物材料发展战略研究

陈曦1(), 袁媛1, 谭业强2(), 刘昌胜1()   

  1. 1.华东理工大学 材料科学与工程学院, 教育部医用生物材料工程研究中心, 上海 200237
    2.国家自然科学基金委员会 工程与材料科学部, 北京 100085
  • 收稿日期:2025-01-06 修回日期:2025-01-17 出版日期:2025-05-20 网络出版日期:2025-01-24
  • 通讯作者: 谭业强, 研究员. E-mail: tanyq@nsfc.gov.cn;
    刘昌胜, 教授. E-mail: liucs@ecust.edu.cn
  • 作者简介:陈 曦(1986-), 女, 副教授. E-mail: chenxi@ecust.edu.cn
  • 基金资助:
    国家自然科学基金(52342203)

Strategic Study on the Development of Inorganic Non-metallic Biomaterials

CHEN Xi1(), YUAN Yuan1, TAN Yeqiang2(), LIU Changsheng1()   

  1. 1. Engineering Research Center for Biomedical Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 200237, China
    2. Department of Engineering and Materials Science, National Natural Science Foundation of China, Beijing 100085, China
  • Received:2025-01-06 Revised:2025-01-17 Published:2025-05-20 Online:2025-01-24
  • Contact: TAN Yeqiang, professor. E-mail: tanyq@nsfc.gov.cn;
    LIU Changsheng, professor. E-mail: liucs@ecust.edu.cn
  • About author:CHEN Xi (1986-), female, associate professor. E-mail: chenxi@ecust.edu.cn
  • Supported by:
    National Natural Science Foundation of China(52342203)

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摘要：

无机非金属生物材料是生物材料的主要类型之一, 在组织修复、肿瘤治疗、药物递送等生物医药领域应用广泛, 为国民生命健康做出了重要贡献。我国无机非金属生物材料的研究日渐繁盛, 但其生产和应用仍处于攻坚克难阶段。为了实现我国无机非金属生物材料的高质量发展, 提高其为国民生命健康保驾护航的硬实力, 本文通过战略研究, 分析了我国无机非金属生物材料研究应用的热点和难点问题。基于目前的发展机遇与挑战, 提出了在材料的独特性能设计、材料生物学效应研究、材料介导的新原理和新机制探索、智能个性化定制、大数据筛选和人工智能设计、标准化评价和监管等方面系统发展无机非金属生物材料的建议, 以期为无机非金属生物医药产品的发展提供指导并积蓄科研和人才力量。

关键词: 无机非金属生物材料, 磷酸钙, 生物陶瓷, 无机纳米材料, 骨修复

Abstract:

Inorganic non-metallic biomaterial is one of main types of biomaterials, which is widely used in biomedical fields such as tissue repair, tumor therapy, and drug delivery., making an important contribution to national life and health. Research on inorganic non-metallic biomaterials in China is flourishing, but their production and application are still in the stage of overcoming difficulties. To realize the high-quality development of China's inorganic non-metallic biomaterials and improve their hard power to protect national life and health, this paper analyzes hotspots and difficult problems in research and application of China's inorganic non-metallic biomaterials by means of strategic study. Based on current development opportunities and challenges, some suggestions are proposed for the development of inorganic non-metallic biomaterials, such as material design for unique performance, research on materiobiology, exploration of new principles and mechanisms mediated by materials, customization by intelligent personalization, design through big data screening and artificial intelligence, and standardization based evaluation/regulation. This aims to provide guidance for development of inorganic non-metallic biomedical products and push forward scientific research while accumulating talent resources.

Key words: inorganic non-metallic biomaterial, calcium phosphate, bioceramic, inorganic nanomaterial, bone repair

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