无机材料学报

• 研究论文 • 上一篇    

等离子喷涂抗菌羟基磷灰石涂层研究

郑学斌1, 季珩1, 黄静琪1, 丁传贤1, 朱梓圆2, 张富强2   

  1. 1. 中国科学院上海硅酸盐研究所, 上海 200050;
    2. 上海第二医科大学附属第九人民医院, 上海 200011
  • 收稿日期:2005-04-29 修回日期:2005-06-14 出版日期:2006-05-20 网络出版日期:2006-05-20

Plasma Sprayed Antibacterial HA Coatings

ZHENG Xue-Bin1, JI Heng1, HUANG JING-Qi1, DING CHUAN-Xian1 ZHU Zi-Yuan2, ZHANG Fu-Qiang2   

  1. 1. Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai
    200050, China;
    2. Shanghai Ninth People's Hospital, Shanghai Second Medical University, Shanghai 200011, China
  • Received:2005-04-29 Revised:2005-06-14 Published:2006-05-20 Online:2006-05-20

摘要: 以磷酸锆载银抗菌剂作为添加剂, 制备真空等离子喷涂抗菌羟基磷灰石(HA)涂层, 并对涂层的形貌、组成、结合强度以及抗菌性能进行研究. 结果表明, 添加抗菌剂的HA涂层形貌没有发生明显改变. 当添加剂含量较大时(10wt%), 涂层中出现少量反应产物CaZr(PO4)2与Na6CaP2O9. 掺入抗菌剂之后涂层的结合强度呈上升趋势, 而且随着抗菌剂百分比的增加, 涂层结合强度随之增大. 含抗菌剂5wt%以上的HA涂层对牙龈单胞卟啉菌(Pg)、具核梭杆菌(Fn)及伴放线杆菌(Aa)具有明显的抗菌作用, 抗菌力大小依次为Pg>Fn>Aa.

关键词: 真空等离子喷涂, HA涂层, 抗菌, 磷酸锆载银抗菌剂

Abstract: HA coatings with silver-zirconium phosphate antimicrobial were prepared via vacuum plasma spraying, and then their surface morphologies, phase compositions, bonding strengths and antibacterial capability were examined. The results obtained show that no obvious change of the surface morphologies is observed after adding antimicrobial in HA coatings. Some new phases such as CaZr(PO4)2 and Na6CaP2O9 appear in the coatings when the antimicrobial
content is high to 10wt%. The bonding strengths of the HA coatings with antimicrobial are higher than that of the HA coating, and the values increase with the increase of antimicrobial content in the coatings. The coatings with the content of antimicrobial equal to or higher than 5% are effectively antibacterial to Pg, Fn and Aa. The antibacterial ability is ordered as Pg>Fn>Aa.

Key words: vacuum plasma spray, HA coating, antibacterial, silver-zirconium phosphate antimicrobial

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