锌锰掺杂Fe3O4纳米颗粒的尺寸可控合成

doi:10.15541/jim20190013

无机材料学报 ›› 2019, Vol. 34 ›› Issue (8): 899-903.DOI: 10.15541/jim20190013 CSTR: 32189.14.10.15541/jim20190013

锌锰掺杂Fe₃O₄纳米颗粒的尺寸可控合成

程田盛^1,^2,³,潘炯⁴,徐鹰鹰^1,^2,³,鲍群群^1,^2,³,胡萍¹(),施剑林¹()

^1. 中国科学院上海硅酸盐研究所, 高性能陶瓷和超微结构国家重点实验室, 上海 200050
^2. 中国科学院大学, 北京 100049
^3. 上海科技大学, 上海 201210
^4. 同济大学, 上海 200092

收稿日期:2019-01-06 出版日期:2019-08-20 网络出版日期:2019-05-29
作者简介:CHENG Tian-Sheng (1994-), male, candidate of Master degree. E-mail: chengtsh@shanghaitech.edu.cn

Synthesis of Zn, Mn doped Fe₃O₄ Nanoparticles with Tunable Size

CHENG Tian-Sheng^1,^2,³,PAN Jiong⁴,XU Ying-Ying^1,^2,³,BAO Qun-Qun^1,^2,³,HU Ping¹(),SHI Jian-Lin¹()

^1. State Key Laboratory of High Performance Ceramics and Superfine Microstructures, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China
^2. University of Chinese Academy of Sciences, Beijing 100049, China
^3. Shanghai Tech University, Shanghai 201210, China
^4. Tongji University, Shanghai 200092, China

Received:2019-01-06 Published:2019-08-20 Online:2019-05-29
Supported by:
National Natural Science Foundation of China(51702349);Science Foundation for Youth Scholar of State Key Laboratory of High Performance Ceramics and Superfine Microstructures(SKL201704);Shanghai Yangfan Program(16YF1412800)

摘要/Abstract

摘要：

锌锰掺杂的Fe₃O₄纳米颗粒具有优异的磁性能, 在生物医药领域有广泛的应用前景。磁性纳米颗粒的尺寸与其磁学性质以及生物磁性应用密切相关。因此, 为了适应不同生物应用对尺寸的需求, 研究其尺寸调控具有重要的意义。在本研究中, 我们采用高温热分解法, 通过加入还原剂1,2-十六烷二醇, 改变金属前躯体和回流时间成功制备了尺寸在5~20 nm的锌锰掺杂Fe₃O₄纳米颗粒。研究发现:强还原剂1,2-十六烷二醇的加入有利于合成小尺寸的纳米颗粒, 而以金属氯化物作为金属前躯体和延长回流时间可以进一步合成更大尺寸的纳米颗粒; 纳米颗粒的饱和磁化强度随着尺寸的增大而增大。

关键词: 锌锰掺杂Fe₃O₄纳米颗粒, 尺寸调控, 磁学性质

Abstract:

Zn, Mn doped Fe₃O₄ magnetic nanoparticles have broad application prospects in biomedicine for their excellent magnetic properties. Therein, the most remarkable property of magnetic nanoparticles is size-dependent biomagnetic applications, and size variation also affect their magnetic characteristics. Therefore, based on the specific requirements of size for various biological applications, it is critical to regulate their size. In this study, we synthesized 5-20 nm Zn, Mn doped Fe₃O₄ magnetic nanoparticles by changing reflux time duration, varying metal precursor and adding oil phase reducing agent (1,2-hexadecanediol). It is found that addition of 1,2-hexadecanediol is beneficial to the formation of smaller nanoparticles, while metal chloride and longer reflux time are helpful to prepare larger particles. Additionally, there exists a positive correlation between particle size and saturation magnetization.

Key words: Zn,Mn-Fe₃O₄ nanoparticles, size regulation, magnetic characteristics

中图分类号:

TQ174

程田盛, 潘炯, 徐鹰鹰, 鲍群群, 胡萍, 施剑林. 锌锰掺杂Fe₃O₄纳米颗粒的尺寸可控合成[J]. 无机材料学报, 2019, 34(8): 899-903.

CHENG Tian-Sheng, PAN Jiong, XU Ying-Ying, BAO Qun-Qun, HU Ping, SHI Jian-Lin. Synthesis of Zn, Mn doped Fe₃O₄ Nanoparticles with Tunable Size[J]. Journal of Inorganic Materials, 2019, 34(8): 899-903.

图/表 5

Fig. 1 TEM images of ZnMn-Fe3O4 nanoparticles and histograms of their size distributions obtained by Fe(acac)3, Mn(acac)2 and Zn(acac)2 with (a, c) and without (b, d) adding 1,2-hexadecanediol

Fig. 2 TEM image (a), histograms of their size distributions (b), high-resolution TEM image (c) and selected area electron diffraction (SAED) pattern (d) of 15 nm-sized ZnMn-Fe3O4 nanoparticles prepared from Fe(acac)3, MnCl2 and ZnCl2

Fig. 3 TEM images of 20 nm-sized ZnMn-Fe3O4 nanoparticles synthesized from Fe(acac)3, MnCl2 and ZnCl2 with different reflux time durations of 1.5 h (a) and 2 h (b), and the corresponding histograms of size distributions of 1.5 h (c) and 2 h (d)

Fig. 4 XRD patterns (a), FT-IR spectra (b) and energy dispersive X-ray spectroscopy (EDS) data (c) of 5 nm, 10 nm, 15 nm, and 20 nm-sized ZnMn-Fe3O4 nanoparticles

Fig. 5 Magnetic hysteresis curve (a) and d-1-dependent Ms curve (b) of 5-20 nm-sized ZnMn-Fe3O4 nanoparticles

参考文献 25

[1]	NOH S H, NA W, JANG J T , et al. Nanoscale magnetism control via surface and exchange anisotropy for optimized ferrimagnetic hysteresis. Nano Letters, 2012,12(7):3716-3721.
[2]	DI CORATO R, BEALLE G, KOLOSNJAJ-TABI J , et al. Combining magnetic hyperthermia and photodynamic therapy for tumor ablation with photoresponsive magnetic liposomes. ACS Nano, 2015,9(3):2904-2916.
[3]	NA H B, SONG I C, HYEON T . Inorganic nanoparticles for MRI contrast agents. Advanced Materials, 2009,21(21):2133-2148. DOI URL
[4]	GAO J H, GU H W, XU B . Multifunctional magnetic nanoparticles: design, synthesis, and biomedical applications. Accounts of Chemical Research, 2009,42(8):1097-1107. DOI URL
[5]	WAN Y, CHENG G, LIU X , et al. Rapid magnetic isolation of extracellular vesicles via lipid-based nanoprobes. Nature Biomedical Engineering, 2017,1:0058.
[6]	LU A H, SALABAS E L, SCHUTH F . Magnetic nanoparticles: synthesis, protection, functionalization, and application. Angew. Chem. Int. Ed., 2007,46(8):1222-1244. DOI URL
[7]	HOCHEPIED J F, PILENI M P . Magnetic properties of mixed cobalt- zinc ferrite nanoparticles. Journal of Applied Physics, 2000,87(5):2472-2478. DOI URL
[8]	ARULMURUGAN R, JEYADEVAN B, VAIDYANATHAN G , et al. Effect of zinc substitution on Co-Zn and Mn-Zn ferrite nanoparticles prepared by co-pecipitation. Journal of Magnetism and Magnetic Materials, 2005,288:470-477.
[9]	JANG J T, NAH H, LEE J H , et al. Critical enhancements of MRI contrast and hyperthermic effects by dopant-controlled magnetic nanoparticles. Angew. Chem. Int. Ed., 2009,48(7):1234-1238.
[10]	DENG H, LI X, PENG Q , et al. Monodisperse magnetic single- crystal ferrite microspheres. Angew. Chem. Int. Ed., 2005,44(18):2782-2785.
[11]	WOO K, LEE H J, AHN J P , et al. Sol-Gel mediated synthesis of Fe₂O₃ nanorods. Advanced Materials, 2003,15(20):1761-1764.
[12]	WU J H, KO S P, LIU H L , et al. Sub 5 nm magnetite nanoparticles: synthesis, microstructure, and magnetic properties. Materials Letters, 2007,61(14/15):3124-3129.
[13]	XIE J, LEE S, CHEN X . Nanoparticle-based theranostic agents . Advanced Drug Delivery Reviews, 2010,62(11):1064-1079. DOI URL
[14]	LEE J H, HUH Y M, JUN Y W , et al. Artificially engineered magnetic nanoparticles for ultra-sensitive molecular imaging. Nature Medicine, 2007,13(1):95-99.
[15]	SINGH M, RAMANATHAN R, MAYES E L H , et al. One-pot synthesis of maghemite nanocrystals across aqueous and organic solvents for magnetic hyperthermia. Applied Materials Today, 2018,12:250-259.
[16]	FORTIN J P, WILHELM C, SERVAIS J , et al. Size-sorted anionic iron oxide nanomagnets as colloidal mediators for magnetic hyperthermia. Journal of the American Chemical Society, 2007,129(9):2628-2635.
[17]	GU H, XU K, XU C , et al. Biofunctional magnetic nanoparticles for protein separation and pathogen detection. Chem. Commun., 2006(9):941-949.
[18]	XU H, AGUILAR Z P, YANG L , et al. Antibody conjugated magnetic iron oxide nanoparticles for cancer cell separation in fresh whole blood. Biomaterials, 2011,32(36):9758-9765.
[19]	LEE J H, JANG J T, CHOI J S , et al. Exchange-coupled magnetic nanoparticles for efficient heat induction. Nature Nanotechnology, 2011,6(7):418-422.
[20]	LARTIGUE L, INNOCENTI C, KALAIVANI T , et al. Water- dispersible sugar-coated iron oxide nanoparticles. An evaluation of their relaxometric and magnetic hyperthermia properties. Journal of the American Chemical Society, 2011,133(27):10459-10472.
[21]	WU L, MENDOZA-GARCIA A, LI Q , et al. Organic phase syntheses of magnetic nanoparticles and their applications. Chemical Reviews, 2016,116(18):10473-10512.
[22]	SUN S H, ZENG H, ROBINSON D B , et al. Monodisperse MFe₂O₄(M = Fe, Co, Mn) nanoparticles. Journal of the American Chemical Society, 2004,126(1):273-279.
[23]	QU Y, LI J, REN J , et al. Enhanced magnetic fluid hyperthermia by micellar magnetic nanoclusters composed of Mn(_x)Zn(₁-_x)Fe, 2014,6(19):16867-16879.
[24]	RONG C B, LI D, NANDWANA V , et al. Size-dependent chemical and magnetic ordering in L10-FePt nanoparticles. Advanced Materials, 2006,18(22):2984-2988.
[25]	JUN Y W, HUH Y M, CHOI J S , et al. Nanoscale size effect of magnetic nanocrystals and their utilization for cancer diagnosis via magnetic resonance imaging. Journal of the American Chemical Society, 2005,127(16):5732-5733.

锌锰掺杂Fe₃O₄纳米颗粒的尺寸可控合成

Synthesis of Zn, Mn doped Fe₃O₄ Nanoparticles with Tunable Size

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