Preparation and Properties of Barium Titanate/Calcium Silicate Composite Bioactive Piezoelectric Ceramics

doi:10.15541/jim20210549

Abstract

Abstract:

Electrical signals generated by piezoelectric materials can promote proliferation and differentiation of osteoblasts, but they can’t induce mineralization, while bioactive materials can induce the deposition of bone like hydroxyapatite in physiological environment, but can not generate electrical signal to promote osteogenesis. Therefore, it is of great significance to develop a composite bioactive piezoelectric material that can not only generate electrical signals, but also induce mineralization and deposition. Here, we used barium titanate as piezoelectric component and calcium silicate as bioactive component to prepare barium titanate/calcium silicate composite as bioactive/piezoelectric ceramics by solid-state sintering method. Piezoelectric properties of the ceramics were tested, and the ability of inducing mineralization was evaluated by in vitro mineralization experiment. The experimental results show that when the content of calcium silicate reaches 30%, the composite ceramics still have certain piezoelectric property (d₃₃=4 pC·N^-1), and can induce the deposition of calcium phosphate in simulated body fluid. Therefore, the combination of barium titanate and calcium silicate can synchronously afford piezoelectric and biological activities, which provides a new choice for bone repair materials.

Key words: barium titanate, calcium silicate, piezoelectricity, bioactivity

CLC Number:

TQ174

WEI Ziqin, XIA Xiang, LI Qin, LI Guorong, CHANG Jiang. Preparation and Properties of Barium Titanate/Calcium Silicate Composite Bioactive Piezoelectric Ceramics[J]. Journal of Inorganic Materials, 2022, 37(6): 617-622.

Figures/Tables 8

Fig. 1 Flow chart of sample preparation

Table 1 Raw material composition of the composite ceramics

	BT	0.9BT 0.1CS	0.8BT 0.2CS	0.7BT 0.3CS	0.6BT 0.4CS	CS
BT/g	2.0000	1.8951	1.7782	1.6481	1.5014	0
CS/g	0	0.1049	0.2215	0.3519	0.4986	2.0000

Fig. 2 XRD patterns (a) and SEM images (b) of composite ceramics

Table 2 Piezoelectric constant d33 of composite ceramics

	BT	0.9BT0.1CS	0.8BT0.2CS	0.7BT0.3CS	0.6BT0.4CS	CS
Before mineralization/(pC·N^-1)	169	44	11	4	1	0
After mineralization/(pC·N^-1)	161	39	8	3	0	0

Fig. 3 Characterization of piezoelectric properties of composite ceramics BT; (b) 0.9BT0.1CS; (c) 0.8BT0.2CS; (d) 0.7BT0.3CS; (e) 0.6BT0.4CS; (f) CS; (g) Variation trend of hysteresis loop; (h) Piezoelectric constant Colorful figures are available on website

Fig. 4 Characterization of in vitro mineralization (a-h) SEM images of different ceramics soaked in SBF for 0 and 14 d; (i-h) EDS spectra of different ceramics soaked in SBF for 14 d SBF: Simulated body fluid

Table 3 Surface element composition of sample after 14 d mineralization

	BT/%	0.9BT0.1CS/%	0.8BT0.2CS/%	0.7BT0.3CS/%
O	59.98	60.53	61.37	7.84
P	-	0.74	0.65	6.81
Si	-	2.57	7.34	0.23
Ca	-	2.04	4.12	8.62
Ti	19.97	17.38	14.42	2.65
Ba	20.05	16.74	12.10	2.71
Ca/P	-	2.76	6.34	1.27

Fig. 5 Cell activity of series solutions of extracts from BT and 0.7BT0.3CS by CCK8 assay *** indicates p<0.01

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