Effect of Dopamine on Hydroxyapatite Deposition for Dental Restoration

doi:10.15541/jim20150262

Abstract

Abstract:

A novel and biomimetic restoration method for teeth by soaking in a simulated oral environment was reported. A biocompatible polydopamine (PDA) layer was deposited on the surface of dentin via dopamine polymerization to functionalize the surface to induce deposition of hydroxyapatite crystals. The samples were characterized by means of XPS, XRD, SEM and EDS. Results show that the coating of polydopamine layer induces the growth of hydroxyl apatite crystal on dentin surface, and improve the binding force between the hydroxyl apatite layer and the dentin surface. The optimized concentration of dopamine solution is 2 mg/mL for the uniform deposition of PDA layer on the dentin surface.

Key words: biomimetic materials, polymerization of dopamine, mineralization of teeth, crystal growth

CLC Number:

R314

XU Jin-Mei, LIU Xin-Ling, GAO Yan-Feng. Effect of Dopamine on Hydroxyapatite Deposition for Dental Restoration[J]. Journal of Inorganic Materials, 2016, 31(1): 95-99.

Figures/Tables 8

Fig. 1 SEM images of the dentin surfaces after being soaked in dopamine solution at different concentrations,(a, b) 0 mg/mL; (c, d) 1 mg/mL; (e, f) 2 mg/mL; (g, h) 3 mg/mL

Fig. 2 XPS wide scan spectra of 37% H3PO4-etched dental slices (a) and the polydopamine coated dentin surface (b)

Table 1 Element content of the dentin, dopamine and enamel-PDA surfaces

	Dentin	Dopamine (theoretical value)	Dentin -PDA
C1s/ at%	7.2	8	11.75
N1s/ at%	2.3	1	2.1
N/C	0.319	0.125	0.179

Fig. 3 XRD patterns of the sample surfaces of 37% H3PO4- etched dental slices (a) and precipitates on the dental surface without (b) or with (c) polydopamine coating after remineralization for 7 d

Fig. 4 SEM images of HAP remineralization of the dentin surface coated with (a, b) or without (c, d) polydopamine after mineralization for 7 d

Table 2 Elements atomic percentage of the surface of hydroxyapatite and precipitates on the dentin surface with or without polydopamine coating after remineralization for 7 days

Element	Surface with PDA	Surface without PDA	HAP
O/at%	69.10	52.88	62.50
P/at%	13.00	17.40	12.50
Ca/at%	17.90	23.81	20.83

Fig. 5 SEM images of the transverse sections of 37% H3PO4-etched dental slices (a) and the preciptates on the enamel surface without (b) or with (c) polydopamine coating after remineralization for 7 d

Fig. 6 SEM images of dentin surface treated by ultrasonic wave which were remineralized with (a, b) or without (c, d) polydopamine coating after mineralization for 7 d

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