Journal of Inorganic Materials

• Research Paper • Previous Articles     Next Articles

In vivo Bioactivity of Ti/HA Bio composites Fabricated by Powder Metallurgy Methods

NING Cong-Qin1; ZHOU Yu2; HUANG Cong-Chun3; GU Ya-Jun3; LI De-Chao3; DAI Ke-Rong1   

  1. 1.Department of Orthopaedics; Shanghai Ninth People s Hospital; Shanghai Second Medical University; Shanghai 200011; China; 2. School of Materials Science and Engineering; Harbin Institute of Technology; Harbin 150001, China; 3. School of Stomatology; Jiamusi University; Jiamusi 154000; China
  • Received:2002-07-17 Revised:2002-09-09 Published:2003-07-20 Online:2003-07-20

Abstract: Ti/HA biocomposites were successfully fabricated by the powder metallurgy method. The in vivo
bioactivities of the biocomposites were investigated. At an early stage of implantation, a fibrous film forms around the pure titanium
implant. And with the increase of implantation time, the fibre tissue disappears gradually, accompanying the formation of new bone. After
6-month implantation, a typical bone-contact interface forms between the pure titanium implant and the surrounding bone. A very
thin film of new bone is observed around the composite with 30% titanium and a big gap exists between the composite and the surrounding
bone at an early stage of implantation, whereas, large quantity of new bone forms around the composites with 50% and 70% titanium. These
three composites all form tight bone-bonding interface with the surrounding bone after 6-month implantation. So it can be concluded
that these Ti/HA composites all exhibit excellent bioactivity. The osteogenic rate of the composite with 30% titanium is distinctly
lower than that of the other two Ti/HA composites. The three Ti/HA composites all have better bioactivity than pure titanium.

Key words: powder metallurgy method, Ti/HA biocomposites, in vivo bioactivity

CLC Number: