无机材料学报

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羟基磷灰石晶种的形貌控制及其对磷酸钙骨水泥的原位增强研究

邵慧芳; 刘昌胜; 黄粤; 曹雪华; 杨海川   

  1. 华东理工大学生物材料研究所 上海 200237
  • 收稿日期:2000-08-07 修回日期:2000-09-01 出版日期:2001-09-20 网络出版日期:2001-09-20

Shape Control of Hydroxyapaptite Crystal Seed and Its Effects on the in-situ Reinforcement of Calcium Phosphate Cement

SHAO Hui-Fang; LIU Chang-Sheng; HUANG Yue; CAO Xue-Hua; YANG Hai-Chuan   

  1. Institute of Biomaterials; East China University of Science and Technology; Shanghai 200237; China
  • Received:2000-08-07 Revised:2000-09-01 Published:2001-09-20 Online:2001-09-20

摘要: 统考察了不同晶种调节剂及其含量对晶种生长的影响,其中包括D-山梨醇,甘露醇,乳糖,葡萄糖,果糖.在此基础上,进一步将合成的晶种应用于磷酸钙骨水泥(简称CPC)的原位增强中,使水化产物晶体之间定向生长和排列,从而达到对CPC进行增强的目的.晶体各向间的表面能不同或表面结构存在差异导致晶体生长速率不同是原位增强的热力学基础.实验结果表明,该方法可使CPC的抗压强度达到76.1MPa,径向抗张强度达到24.5MPa.

关键词: 羟基磷灰石, 晶种, 磷酸钙骨水泥, 原位增强

Abstract: The effects of the contents of different regulators including D-sorbital, mannose, galactose, glucose, and fructors on the growth of
hydroxyapaptite crystal seeds were studied, and the crystal seeds obtained were then applied to the in-situ reinforcement of calcium phosphate
cement. The experimental results show that the discrepancies of the surface energy and structure of the crystal of different orientations lead to
different growth rates, and this is the thermodynamic foundation of its in situ reinforcement. The compressive strength of the hardening
body is up to 76.1 MPa, the diamentral tensile strength is up to 24.5 MPa.

Key words: hydroxyapatite, crystal seed, calcium phosphate cement, in-situ reinforcement

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