掺杂TiO2纳米管的润湿性能与体外生物活性

doi:10.3724/SP.J.1077.2010.09749

无机材料学报 ›› 2010, Vol. 25 ›› Issue (7): 775-779.DOI: 10.3724/SP.J.1077.2010.09749 CSTR: 32189.14.SP.J.1077.2010.09749

掺杂TiO₂纳米管的润湿性能与体外生物活性

黄麟^1,2, 宁聪琴², 丁冬雁¹, 白硕¹, 秦锐¹, 李明¹, 毛大立¹

(1. 上海交通大学材料科学与工程学院微电子材料与技术研究所, 上海200240; 2. 中国科学院上海硅酸盐研究所高性能陶瓷和超微结构国家重点实验室, 上海200050)

收稿日期:2009-11-01 修回日期:2009-03-05 出版日期:2010-07-20 网络出版日期:2010-06-10
基金资助:
The National High technology Research and Development Program (863 program) of China (2006AA02A1); Shanghai Pujiang Program (07PJ14047, 07PJ147092)

Wettability and In Vitro Bioactivity of Doped TiO₂Nanotubes

HUANG Lin ^{1, 2}, NING Cong-Qin², DING Dong-Yan¹, BAI Shuo¹, QIN Rui ¹, LI Ming ¹, MAO Da-Li¹

(1. Lab of Microelectronic Materials and Technology, School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, China; 2. State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China)

Received:2009-11-01 Revised:2009-03-05 Published:2010-07-20 Online:2010-06-10
Supported by:
The National High technology Research and Development Program (863 program) of China (2006AA02A1); Shanghai Pujiang Program (07PJ14047, 07PJ147092)

摘要/Abstract

摘要：

以低模量钛合金(Ti35Nb和Ti35Nb15Zr)为阳极氧化基材, 采用表面阳极氧化方法制备出铌元素和锆元素掺杂的非晶TiO₂纳米管阵列, 比较了掺杂前后纳米管的润湿性能与体外生物活性. 实验结果表明, 加入铌和锆元素可减小TiO₂纳米管的管径, 并有助于增大TiO₂纳米管的长度. TiO₂纳米管表现出与未氧化前的金属基材所不同的疏水行为. 掺杂TiO₂纳米管的润湿性随着掺杂元素的变化而变化, 铌元素的掺杂可使TiO₂纳米管的润湿性改善, 铌元素和锆元素共同掺杂对润湿性的改善作用更明显. 在模拟体液(SBF)中浸泡后, 掺杂TiO₂纳米管可快速诱导磷灰石的形成. 铌锆元素共同掺杂的纳米管在初始浸泡阶段呈现较快的磷灰石沉积速率. 上述研究结果表明, 可以通过基材合金化设计来调控或修饰材料表面的亲水或疏水性能, 从而探索掺杂TiO₂纳米管的生物学性能.

关键词: 阳极氧化, 纳米管, 润湿性, 生物活性

Abstract:

With low-modulus alloys of Ti35Nb and Ti35Nb15Zr as the anodization substrates, amorphous TiO₂ nanotube arrays doped by Nb and Zr elements were fabricated through a surface anodization method. The wettability and in vitro bioactivity of the doped TiO₂ nanotubes and undoped nanotubes were investigated. Experimental results indicated that the existence of Nb and Zr elements in the anodic oxides could refine the diameter of the nanotubes and help to grow longer nanotubes. All of the as-anodized nanotubes demonstrated a hydrophobic behavior, which was different from those of the metallic substrate surface. The wettability of the TiO₂-based nanotubes varied with the type of the substrate or dopant element. The doping with Nb element could improve the wetting behavior of the TiO₂nanotubes. And simultaneous doping with Nb and Zr elements could have more significant improvement in the wetting behavior. After immersion in simulated body fluids (SBF) the doped TiO₂ nanotubes could induce a quick apatite formation. The Nb/Zr doped nanotubes presented quicker apatite formation rate than the Ti-Nb-O nanotubes did at the initial immersion stage. The above findings make it possible to further control or modify the wettability toward either hydrophobic or hydrophilic surfaces, and explore related biological properties of the doped nanotubes.

Key words: anodization, nanotubes, wettability, bioactivity

中图分类号:

TQ153

黄麟, 宁聪琴, 丁冬雁, 白硕, 秦锐, 李明, 毛大立. 掺杂TiO₂纳米管的润湿性能与体外生物活性[J]. 无机材料学报, 2010, 25(7): 775-779.

HUANG Lin, NING Cong-Qin, DING Dong-Yan, BAI Shuo, QIN Rui, LI Ming, MAO Da-Li. Wettability and In Vitro Bioactivity of Doped TiO₂Nanotubes[J]. Journal of Inorganic Materials, 2010, 25(7): 775-779.

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掺杂TiO₂纳米管的润湿性能与体外生物活性

Wettability and In Vitro Bioactivity of Doped TiO₂Nanotubes

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