无机材料学报

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卵磷脂对生物活性玻璃表面改性的研究

赵娜如1, 2, 3, 王迎军1, 2, 3, 杜 昶1, 2, 3, 邓延婕2, 蔡 岩2   

  1. (华南理工大学1. 特种功能材料教育部重点实验室; 2.材料科学与工程学院; 3.生物医学工程研究院, 广州510641)
  • 收稿日期:2008-11-05 修回日期:2009-04-01 出版日期:2009-09-20 网络出版日期:2009-09-20

Surface Modification of Bioglass with Phosphatidyl Cholines

ZHAO Na-Ru1, 2, 3, WANG Ying-Jun 1, 2, 3, Du Chang1,2, 3, DENG Yan-Jie2, CAI Yan2   

  1. (1. Key Laboratory of Specially Functional Materials, Ministry of Education, South China University of Technology, Guangzhou 510641, China; 2. College of Materials Science and Engineering, South China University of Technology, Guangzhou 510641, China; 3. Institute of Biomedical Engineering, South China University of Technology, Guangzhou 510641, China )
  • Received:2008-11-05 Revised:2009-04-01 Published:2009-09-20 Online:2009-09-20

摘要: 采用卵磷脂对生物活性玻璃粉体表面进行改性处理, 并研究了生物活性玻璃与卵磷脂的相互作用. 热分析(TG/DSC)、傅立叶变换红外光谱(FTIR)分析表明, 卵磷脂在生物活性玻璃表面附着,通过氢键等弱键相互作用. 表面改性后的生物活性玻璃粉体与壳聚糖复合后, 复合材料的力学强度与未处理的相比有明显提高. 扫描电子显微镜(SEM)结果显示, 经处理后的生物活性玻璃粉体在壳聚糖中分散均匀, 两者结合紧密, 表明卵磷脂改性可以有效地提高生物活性玻璃粉体与壳聚糖有机基质的界面结合强度.

关键词: 卵磷脂, 生物活性玻璃, 表面改性

Abstract: Bioglass powders were treated with phosphatidyl cholines, and the interactions between bioglass and phosphatidyl cholines were studied by thermal analysis and fourier transform infrared spectroscopy (FTIR). The phosphatidyl cholines are adhered on the bioglass surface through weak interactions such as hydrogen bonds. Surface modification of bioglass particles improves the compressive strength of the bioglass/chitosan composites. SEM observation indicates a uniform distribution of modified bioglass particles in the chitosan matrix. The results suggest that the surface modification by phosphatidyl cholines can effectively enhance the interfacial interaction between bioglass particles and chitosan matrix.

Key words: phosphatidyl choline, bioglass, surface modification

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