Surface Topology and Cytocompatibility of Polyphosphate Macroporous Ceramics with Recoating

doi:10.3724/SP.J.1077.2014.13268

Abstract

Abstract: Polyphosphate porous ceramics were prepared and then recoated with thinner slurry. Macroporous characteristics, surface topology and cytocompatibility of samples before and after being recoated was evaluated using scan emission microscope (SEM), the Archimedes drainage method and the cells cultivation test in vitro. The results show that the pore wall thickness of samples increases with the increase of coating times, which slighty decreases their porosity. After being coated for 3 times, however, the macroporous morphology does not change obviously and the porosity is still more than 80%. Simultaneously, plenty of micropores with about 1–2 μm diameter are observed on the wall surfaces of samples. Furthermore, these surfaces are in favor of rabbit bone mesenchymal stem cells (RBMSC) adhesion, spreading and proliferation. These results indicate that the recoating process, especially repeated for 3 times, alters the surface topology of samples and enhances their cytocompatibility, but not sacrifices their macroporous characteristics.

Key words: recoating, polyphosphate, macroporous, surface topology, cytocompatibility

CLC Number:

TQ174
R318

LIU Bin, DONG Yin-Sheng, WU Hong-Yan, SU Jing, LIN Ping-Hua, GUO Zong-Ke. Surface Topology and Cytocompatibility of Polyphosphate Macroporous Ceramics with Recoating[J]. Journal of Inorganic Materials, 2014, 29(2): 179-184.

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