Preparation of Polyphosphate Porous Bioceramics and in vitro Cytocompatibility

doi:10.3724/SP.J.1077.2011.00759

Abstract

Abstract: The porous ceramics were prepared by the foam impregnation technology using Al₂O₃-MgO-P₂O₅ as binder. Porous morphology, crystalline phase, porosity, and mechanical property were investigated by using scaning electron microscope (SEM), X-ray diffraction (XRD), Archimedes drainage method, and compression tests. It was found that Al₂O₃-MgO-P₂O₅phosphate promoted the sintering of ceramics, and improved coating of ceramic slurry over the foams uniformly. The obtained ceramics have connective, uniform pore structures with macro-pores of about 100-500μm in diameter and micro-pores of about 3μm in diameter. Their average porosity and compressive strength were 85.9%±1.6% and (1.04±0.15) MPa respectively. Although sintered porous ceramics were polyphosphates composed of HA, β-Ca₂P₂O₇ and a few phases including Al and Mg. They had no cytotoxicity and provoked the proliferation and differentiation of marrow stromal stem cells in vitro. Thus it can be concluded that this kind of porous ceramics has good cellular affinity and cytocompatibility.

Key words: polyphosphates, porous ceramics, Al₂O₃-MgO-P₂O₅, cytocompatibility

CLC Number:

TQ174
R318

LIU Bin, DONG Yin-Sheng, LIN Ping-Hua, ZHANG Jun, SU Jing. Preparation of Polyphosphate Porous Bioceramics and in vitro Cytocompatibility[J]. Journal of Inorganic Materials, 2011, 26(7): 759-764.

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