别嘌醇插层Zn/Al-NO3-LDH复合材料的组装及缓释性能

doi:10.3724/SP.J.1077.2011.01293

无机材料学报 ›› 2011, Vol. 26 ›› Issue (12): 1293-1298.DOI: 10.3724/SP.J.1077.2011.01293 CSTR: 32189.14.SP.J.1077.2011.01293

别嘌醇插层Zn/Al-NO₃-LDH复合材料的组装及缓释性能

杜宝中, 邰炜, 骆薇, 彭振国

(西安理工大学应用化学系, 西安 710048)

收稿日期:2011-01-09 修回日期:2011-03-14 出版日期:2011-12-20 网络出版日期:2011-11-11
基金资助:
西安市工业科技攻关项目(YF07058)

Assembly and Release Behavior of Allopurinol Intercalated Zn/Al-NO₃-LDH Composite

DU Bao-Zhong, TAI Wei, LUO Wei, PENG Zhen-Guo

(Department of Applied Chemistry,Xi’an University of Technology, Xi’an 710048, China)

Received:2011-01-09 Revised:2011-03-14 Published:2011-12-20 Online:2011-11-11
Supported by:
Science and Technique Foundation of Xi’an (YF07058)

摘要/Abstract

摘要： 以共沉淀法和离子交换法制备别嘌醇插层Zn/Al-NO₃-LDH复合材料, 结合XRD、FT-IR、TG-DTA分析表明, 别嘌醇进入LDH层间与层板相互作用形成超分子结构, 提高了别嘌醇的耐酸性和热稳定性, 且共沉淀法制备的别嘌醇插层LDH具有良好的缓释性能. 提出了共沉淀法制备有机分子插层LDH过程中, 存在易于客体进行离子交换和包埋的溶胶-凝胶中间形态的假设, 可提高有机分子插层量.

关键词: 别嘌醇, 水滑石, 插层组装, 复合材料, 缓释

Abstract: Allopurinot intercalated Zn/Al-NO₃-LDH composite materials were prepared by coprecipitation and ion exchange methods. It was found by XRD, FT-IR and TG-DTA analysis that allopurinol were intercalated into the LDH layers and formed a supramolecular structure in the reaction with laminate. The structure could improved allopurinol acid resistance and thermal stability. The allopurinol intercalated LDH preparaed by coprecipitation method has an excellent sustained-release performance. It was supposed that the intercalation capacity of organic molecules was increased by a Sol-Gel intermediate which was easy for the objects to be ion-exchanged and embedded during the organic molecules intercalating into the LDH layers by coprecipitation method.

Key words: allopurinol, LDH, intercalating assembly, composite, sustained-release

中图分类号:

TQ426

杜宝中, 邰炜, 骆薇, 彭振国. 别嘌醇插层Zn/Al-NO₃-LDH复合材料的组装及缓释性能[J]. 无机材料学报, 2011, 26(12): 1293-1298.

DU Bao-Zhong, TAI Wei, LUO Wei, PENG Zhen-Guo. Assembly and Release Behavior of Allopurinol Intercalated Zn/Al-NO₃-LDH Composite[J]. Journal of Inorganic Materials, 2011, 26(12): 1293-1298.

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别嘌醇插层Zn/Al-NO₃-LDH复合材料的组装及缓释性能

Assembly and Release Behavior of Allopurinol Intercalated Zn/Al-NO₃-LDH Composite

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