不锈钢表面渗铜扩散复合处理合金层的抗菌性能研究

doi:10.3724/SP.J.1077.2012.00519

无机材料学报 ›› 2012, Vol. 27 ›› Issue (5): 519-523.DOI: 10.3724/SP.J.1077.2012.00519 CSTR: 32189.14.SP.J.1077.2012.00519

不锈钢表面渗铜扩散复合处理合金层的抗菌性能研究

张翔宇, 蒋立, 黄晓波, 马永, 范爱兰, 唐宾

(太原理工大学表面工程研究所, 太原 030024)

收稿日期:2011-06-27 修回日期:2011-08-12 出版日期:2012-05-10 网络出版日期:2012-03-31
作者简介:张翔宇(1984-), 男, 博士研究生. E-mail: zxyclwl@126.com
基金资助:
山西省科技攻关项目(20110321051);国家自然科学基金(51171125);山西省研究生优秀创新项目(20103024)

Improvement of Antibacterial Properties of Stainless Steel by Combining Plasma Cu and Thermal Diffusion

ZHANG Xiang-Yu, JIANG Li, HUANG Xiao-Bo, MA Yong, FAN Ai-Lan, TANG Bin

(Research Institute of Surface Engineering, Taiyuan University of Technology, Taiyuan 030024, China)

Received:2011-06-27 Revised:2011-08-12 Published:2012-05-10 Online:2012-03-31
About author:ZHANG Xiang-Yu. E-mail: zxyclwl@126.com
Supported by:
Programs for Science and Technology Development of Shanxi (20110321051);National Natural Science Foundation of China(51171125);Graduate Innovation Project of Shanxi Province (20103024)

摘要/Abstract

摘要：

采用等离子表面合金化及辉光轰击热扩散复合处理技术在不锈钢表面进行了铜合金化处理. 利用薄膜密贴法对改性层的抗菌性能进行了测试. 通过扫描电子显微镜(SEM)、辉光放电光谱分析仪(GDOES)和X射线光电子能谱(XPS)等手段, 研究了铜合金层的微观组织、化学成分分布及抗菌前后表面铜的价态变化. 结果表明, 铜合金层对大肠杆菌(E. coli)和金黄色葡萄球菌(S. aureus)都展现了优良抗菌性能; 合金层表面铜约为5.7wt%, 合金层厚度约2.7 µm; 表面铜合金化不锈钢与菌液接触后, 不锈钢表面的铜元素以铜离子析出, 并且与试验菌种发生作用, 杀灭试验细菌.

关键词: 不锈钢, 复合处理, 铜合金层, 抗菌性能

Abstract:

The duplex treatment consisting of plasma surface alloyed with copper followed by thermal diffusion under the bombardment of glow was carried out on AISI 304 stainless steel in order to improve its antibacterial properties. The antibacterial properties against Gram-negative E.coli ATCC10536 and Gram-positive S.aureus ATCC25923 of the untreated and duplex-treated stainless steel were investigated by using a spread plate method. The microstructure, chemical composition and the change of the chemical state of copper on the surface of the duplex treated stainless steel were characterized using scanning electron microscope (SEM), glow discharge optical emission spectroscope (GDOES) and X-ray photoelectron spectroscope (XPS). The results show that the antibacterial rates gradually rise with increase of the contact time between the bacteria and the copper-alloyed stainless steel, and the alloyed surface exhibits excellent antibacterial properties against both E.coli and S.aureus within 12 h. The copper concentration on the alloyed surface reaches to 5.7wt% and the thickness of the alloyed layer is about 2.7 µm. XPS analysis indicated that Cuions was released when the copper-alloyed surface contacted with bacterial solution, which led to death of the bacteria.

Key words: stainless steel, duplex treatment, copper alloyed layer, antibacterial property

中图分类号:

TQ174

张翔宇, 蒋立, 黄晓波, 马永, 范爱兰, 唐宾. 不锈钢表面渗铜扩散复合处理合金层的抗菌性能研究[J]. 无机材料学报, 2012, 27(5): 519-523.

ZHANG Xiang-Yu, JIANG Li, HUANG Xiao-Bo, MA Yong, FAN Ai-Lan, TANG Bin. Improvement of Antibacterial Properties of Stainless Steel by Combining Plasma Cu and Thermal Diffusion[J]. Journal of Inorganic Materials, 2012, 27(5): 519-523.

图/表 5

Table 1 Calculated antibacterial rate of Cu-alloyed stainless steel after a designated contact time with bacterial

Bacterial kinds	Antibacterial rates
Bacterial kinds	1 h	3 h	12 h
E．coli	80%	96%	99.9%
S．aureus	73%	94%	99.9%

图1 对照不锈钢和铜合金化不锈钢分别对大肠杆菌(a、b)和金黄色葡萄球菌(c、d)抗菌性能检测效果图

Fig. 1 Photos of antibacterial effects of the tested stainless steel against E.coli: (a) control and (b) Cu-alloyed, and S.aureus: (c) control and (d) Cu-alloyed

图2 铜合金化不锈钢表面形貌照片及面扫描EDS分析

Fig. 2 SEM image of Cu-alloyed stainless steel and corresponding EDS analysis

图3 铜合金层各元素成分分布

Fig. 3 Alloy elements distribution of the Cu-alloyed layer

图4 与细菌作用前(a)、后(b)合金化不锈钢表面Cu2p3/2的XPS能谱

Fig. 4 XPS spectra of Cu2p3/2 for Cu-alloyed stainless steel before (a) and after (b) contacting the bacterial

参考文献 18

[1]	刘永前, 南黎, 陈德敏, 等(LIU Yong-Qian, et al). 含铜马氏体抗菌不锈钢的研究. 稀有金属材料与工程(Rare Metal Mat. Eng.), 2008, 37(8): 1380-1383.
[2]	杨柯, 董加胜, 陈四红, 等. 含Cu抗菌不锈钢的工艺与耐蚀性能. 材料研究学报, 2006, 20(5): 523-527.
[3]	刘超锋. 整体系抗菌不锈钢材料及其制造技术. 铸造技术, 2007, 28(9): 1262-1265.
[4]	Hong I T, Koo C H. Antibacterial properties, corrosion resistance and mechanical properties of Cu-modified SUS 304 stainless steel. Materials Science and Engineering A, 2005, 393(1/2): 213-222.
[5]	张志霞, 林刚, 徐洲. 含铜铁素体抗菌不锈钢中抗菌相的析出行为. 材料热处理学报, 2008, 29(5): 93-96.
[6]	Wan Y Z, Raman S, He F, et al. Surface modification of medical metals by ion implantation of silver and copper. Vacuum, 2007, 81(9):1114-1118.
[7]	Dan Z G, Ni H W, Xu B F, et al. Microstructure and antibacterial properties of AISI 420 stainless steel implanted by copper ions. Thin Solid Films, 2005, 492(1/2): 93-100.
[8]	Tian X B, Wang Z M, Yang S Q, et al. Antibacterial copper- containing titanium nitride films produced by dual magnetron Sputtering. Surface and Coatings Technology, 2007, 201(19/20): 8606-8609.
[9]	Kuo Y C, Lee J W, Wang C J, et al. The effect of Cu content on the microstructures, mechanical and antibacterial properties of Cr–Cu–N nanocomposite coatings deposited by pulsed DC reactive magnetron sputtering. Surface and Coatings Technology, 2007, 202(4-7): 854-860.
[10]	李东, 许伯藩, 倪红卫, 等. 沉积扩散法制备不锈钢抗菌渗铜层的研究. 金属热处理, 2005, 30(2): 8-11.
[11]	Xu Z, Liu X, Zhang P, et al. Double glow plasma surface alloying and plasma nitriding. Surface and Coatings Technology, 2007, 201(9/10/11): 4822-4825.
[12]	Tang T, Wu P Q, Li X Y, et al. Tribological behavior of plasma Mo–N surface modified Ti-6Al-4V alloy. Surface and Coating Technology, 2004, 179(2/3): 333-339.
[13]	徐重. 等离子表面冶金学. 北京: 科学出版社. 2008.
[14]	Noyce J O, Michels H, Keevil C W. Potential use of copper surfaces to reduce survival of meticillin-resistant staphylococcus aureus in the healthcare environment. Journal of Hospital Infection, 2006, 63(3): 289-297.
[15]	TAN San-Xiang, TAN Shao-Zao, LIU Ying-Liang, et al. Preparation and antibacterial property of copper-loaded activated carbon microspheres. Journal of Inorganic Materials, 2010, 25(3): 299-305.
[16]	CHEN Jun-Hua, WANG Fei, CHENG Nian-Shou, et al. Characterization and antibacterial ability of copper-modified hexagonal mesoporous silica in situ. Journal of Inorganic Materials, 2009, 24(4): 695-701.
[17]	Li N, Liu Y Q, Lu M Q, et al. Study on antibacterial mechanism of copper-bearing austenitic antibacterial stainless steel by atomic force microscopy. J. Mater. Sci: Mater. Med., 2008, 19(9): 3057-3062.
[18]	Ruparelia J P, Chatterjee A K, Duttagupta S P, et al. Strain specificity in antimicrobial activity of silver and copper nanoparticles. Acta Biomaterialia, 2008, 4(3): 707-716.

不锈钢表面渗铜扩散复合处理合金层的抗菌性能研究

Improvement of Antibacterial Properties of Stainless Steel by Combining Plasma Cu and Thermal Diffusion

RichHTML

PDF (PC)

可视化

被引次数

摘要/Abstract

引用本文

使用本文

图/表 5

参考文献 18

相关文章 15

编辑推荐

Metrics

本文评价

[1]	盛丽丽, 常江. 光/磁热Fe₂SiO₄/Fe₃O₄双相生物陶瓷及其复合电纺丝膜制备及抗菌性能研究[J]. 无机材料学报, 2022, 37(9): 983-990.
[2]	王恩典, 常江. 钼掺杂铜硅钙石的制备及其抗菌性能和细胞相容性研究[J]. 无机材料学报, 2021, 36(7): 738-744.
[3]	刘玉玲, 王瑞莉, 李楠, 刘梅, 张青红. ZnO介晶填料的制备及其齿科复合树脂的性能[J]. 无机材料学报, 2019, 34(10): 1077-1084.
[4]	王有和, 王晓东, 徐经纬, 孙洪满, 吴成成, 阎子峰, 季生福. 酸碱复合处理制备多级孔ZSM-5分子筛及其甲醇制汽油反应性能[J]. 无机材料学报, 2018, 33(11): 1193-1200.
[5]	魏磊, 黄彦. 炭辅助的固态粒子烧结工艺制备多孔TiO₂/不锈钢膜[J]. 无机材料学报, 2015, 30(4): 427-431.
[6]	魏磊, 俞健, 胡小娟, 黄彦. 烧结应力的缓冲及Al₂O₃/不锈钢微滤膜的制备[J]. 无机材料学报, 2014, 29(4): 433-437.
[7]	谭英, 谭帼馨, 宁成云, 容锡沧, 张余, 周蕾. 聚多巴胺修饰钛表面纳米载银及其抗菌和细胞相容性[J]. 无机材料学报, 2014, 29(12): 1320-1326.
[8]	李帅, 何迪, 刘晓鹏, 张超, 王树茂, 于庆河, 邱昊辰, 蒋利军. 316L不锈钢基体氧化铝涂层的氢渗透性能[J]. 无机材料学报, 2013, 28(7): 775-779.
[9]	李丹, 陈运法. 离子液体/磷酸锆抗菌材料的制备及耐热性研究[J]. 无机材料学报, 2011, 26(11): 1193-1198.
[10]	宫璐, 沈静, 李全新. C12A7-O^-材料抗菌性能及机理研究[J]. 无机材料学报, 2010, 25(9): 942-946.
[11]	陈君华,王飞,程年寿,丁志杰,伏再辉,银董红. 铜原位改性HMS材料的表征及抗菌性能[J]. 无机材料学报, 2009, 24(4): 695-701.
[12]	戴晋明,侯文生,魏丽乔,贾虎生. 载银锌4A沸石抗菌剂抗变色性能的研究[J]. 无机材料学报, 2008, 23(5): 1011-1015.
[13]	邹俭鹏,阮建明,周忠诚,黄伯云,陈启元. 316L纤维尺寸和含量对HA-ZrO₂(CaO)/316L纤维复合生物材料性能的影响[J]. 无机材料学报, 2007, 22(5): 1001-1006.
[14]	韩晓建,黄争鸣,何创龙,刘玲,董国华,吴庆生. 聚碳酸酯/TiO₂超细纤维的制备与表征[J]. 无机材料学报, 2007, 22(3): 407-412.
[15]	李吉东,李玉宝,王学江,杨维虎,周钢. 载铜锌纳米羟基磷灰石的抗菌性能及机理研究[J]. 无机材料学报, 2006, 21(1): 162-168.