Preparation and in vitro Properties of CaSiO3/TiO2 Composite Bioceramics

doi:10.3724/SP.J.1077.2013.12138

Abstract

Abstract:

CaSiO₃ has attracted much attention as a bone substitute due to its strong ability to induce the formation of bonelike apatite in vitro. However, its poor chemical stability, biocompatibility, sintering and mechanical properties limit its further applications. In the present study, CaSiO₃/TiO₂ composites with initial CaSiO₃/TiO₂molar ratios at 2:1, 3:1 and 5:1 were prepared by solid-state reaction method. CaSiO₃/TiO₂ ceramics sintered at 1100℃ with the crystal phases of CaSiO₃ and CaTiSiO₅were found to have optimistic sintering behavior, mechanical properties and degradability compared with pure CaSiO₃ ceramics. With the CaSiO₃content increased, the mechanical properties were enhanced while the in vitro bioactivity and biodegradability decreased. All these results suggest that CaSiO₃/TiO₂ composite ceramics maybe a prospective candidate for bone repair and the properties can be adjusted by changing their chemical compositions to adapt to bone regeneration.

Key words: Ti-containing silicate ceramics, CaSiO₃, TiO₂, apatite formation ability, degradability

CLC Number:

TB332

YU Hui-Xian, NING Cong-Qin. Preparation and in vitro Properties of CaSiO₃/TiO₂ Composite Bioceramics[J]. Journal of Inorganic Materials, 2013, 28(1): 69-73.

Figures/Tables 7

Fig. 1 XRD patterns of the CaSiO3/TiO2 ceramics sintered at 1100℃

Table 1 Porosity, bending strength and Young’s modulus of the β-CaSiO3/TiO2 ceramics sintered at 1100℃

Sample	Porosity/%	Bending strength /MPa	Young’s modulus /GPa
CTS^*	24±0.1	63±14.4	35±2.7
CS2T1	8±1.1	124±22.6	79±9.5
CS3T1	6±0.7	135±6.3	92±9.2
CS5T1	4±0.9	172±21.7	97±4.3
CS^*	12±0.1	109±4.9	53±4.1

Fig. 2 SEM images of the CaSiO3/TiO2 ceramics before and after soaking in SBF for 14 d

Table 2 P content of the CaSiO3/TiO2 composite ceramics after soaking in SBF for 14 d determined by EDS

Sample	P content/at%
CS2T1	0.21±0.03
CS3T1	0.20±0.05
CS5T1	0.16±0.02

Fig. 3 Weight loss results of the CaSiO3/TiO2 ceramics after soaking in Tris-HCl for 28 d

Fig. 4 Changes in element concentrations in the collected Tris-HCl

Fig.5 Change in pH value of the collected Tris-HCl

References 16

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Preparation and in vitro Properties of CaSiO₃/TiO₂ Composite Bioceramics

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