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无机材料学报

无机材料学报

• 研究论文 •    下一篇

骨和牙中磷酸钙的矿化过程及其模拟的研究进展

欧阳健明1,2; 郑辉1   

  1. 1. 暨南大学生物矿化与结石病防治研究所, 广州 510632; 2. 南京大学配位化学国家重点实验室, 南京 210093
  • 收稿日期:2004-06-07 修回日期:2004-07-07 出版日期:2005-07-20 网络出版日期:2005-07-20

Progress of Biomineralization Process of Calcium Phosphate in Bone and Teeth

OUYANG Jian-Ming1,2; ZHENG Hui1   

  1. 1. Institute of Biomineralization and Lithiasis Research; Jinan University; Guangzhou 510632; China; 2. State Key Laboratory of Coordination Chemistry; Nanjing University; Nanjing 210093; China
  • Received:2004-06-07 Revised:2004-07-07 Published:2005-07-20 Online:2005-07-20

PDF (PC)

1786

被引次数

26

摘要： 磷酸钙是生物体中的主要矿化物.本文综述了骨和牙中磷酸钙的矿化过程及其体外模拟的研究进展,比较了两者在成分、结构、有机基质和形成机理等方面的异同.从分子识别、晶格匹配、静电作用等方面讨论了矿化过程中有机基质对磷酸钙晶体生长的调制作用.

关键词: 磷酸钙, 羟磷灰石, 生物矿化, 骨牙

Abstract: Calcium phosphates are the main biominerals in organism. The biomineralization process of various calcium
phosphates in bone and teeth in vivo and in vitro was reviewed in this paper. The composition, structure, organic matrix and formation mechanisms of bone
and teeth were introduced and compared. The modulation of organic matrix on the growth of calcium phosphate was discussed about the molecular recognition,
lattice matching and electrostatic interaction at the organic/inorganic interface.

Key words: calcium phosphate, hydroxyapatite, biomineralization, bone, teeth

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