Spark Plasma Sintering of Bioactive Ca2MgSi2O7 Ceramics

doi:10.15541/jim20160614

Abstract

Abstract:

The bio-ceramics based on Ca and Si have wide development prospect in biomedical, which is attributed to their outstanding bioactivity and cytocompatibility. However, how to improve its sinterability is a key problem to be solved. In this study, pure Ca₂MgSi₂O₇ powders were prepared via a co-precipitation method, and then were sintering by spark plasma sintering (SPS) technique. The phase and the morphology of the resulting products were characterized by X-ray diffraction (XRD) and scanning electron microscope (SEM), respectively. The relative density and the bioactivity were also investigated by Archimedean method and simulated body fluid (SBF) soaking method, respectively. Experimental results showed that the Ca₂MgSi₂O₇ ceramics with density of about 99% could be achieved by spark plasma sintering at 1170℃ for 5 min under 70 MPa. After soaking in the simulated body fluid for 3 d, phosphate precipitation was observed on the surface of the ceramics, while bone-like hydroxyapatite was formed until 7 d soaking, indicating that the Ca₂MgSi₂O₇ ceramics prepared by SPS have good bioactivity to induce the sedimentation of bone-like hydroxyapatite.

Key words: akermanite, spark plasma sintering, bioactivity

CLC Number:

TB383
TQ028

WANG Ming-Hui, ZHONG Hong-Bin, FAN Yu-Chi, CHEN Ting. Spark Plasma Sintering of Bioactive Ca₂MgSi₂O₇ Ceramics[J]. Journal of Inorganic Materials, 2017, 32(8): 825-830.

Figures/Tables 7

Fig. 1 XRD patterns for Ca2MgSi2O7 powder and ceramics sintered at different temperatures

Fig. 2 Relative density of Ca2MgSi2O7 ceramics as a function of sintering temperature

Fig. 3 SEM images of the fracture surface of Ca2MgSi2O7 ceramics sintered at different temperatures(a) 950℃; (b) 1050℃; (c) 1100℃; (d) 1130℃; (e) 1170℃

Fig. 4 XRD patterns of Ca2MgSi2O7 ceramics before and after soaking in SBF solution for various periods

Fig. 5 FTIR spectra of Ca2MgSi2O7 ceramics soaked in SBF for various periods

Fig. 6 SEM images of Ca2MgSi2O7 ceramics soaked in SBF for various periods(a, e) 1 d; (b, f) 3 d; (c g) 7 d; (d, h) 14 d

Fig. 7 Changes of ion concentrations and pH of the SBF solution after soaking with Ca2MgSi2O7 ceramics for various periods

References 16

[1]	RAZAVI M, FATHI M, SAVABI O, et al.Controlling the degradation rate of bioactive magnesium implants by electrophoretic deposition of akermanite coating.Ceram. Int., 2014, 40: 3865-3872.
[2]	ZHAI W, LU H, WU C, et al.Stimulatory effects of the ionic products from Ca-Mg-Si bioceramics on both osteogenesis and angiogenesis in vitro.Acta Biomater., 2013, 9: 8004-8014.
[3]	倪似愚, 硅酸钙及其复合生物材料的制备与性能研究. 上海: 中国科学院上海硅酸盐研究所博士学位论文, 2006.
[4]	吴成铁, Ca-Si-M系列硅酸盐生物陶瓷的制备及性能研究. 上海: 中国科学院上海硅酸盐研究所博士学位论文, 2006.
[5]	XIA L, YIN Z, MAO L, et al.Akermanite bioceramics promote osteogenesis, angiogenesis and suppress osteoclastogenesis for osteoporotic bone regeneration.Sci. Rep., 2016, 6: 22005.
[6]	WU C, CHANG J.Synthesis and apatite-formation ability of akermanite. Mater. Lett., 2004, 58: 2415-2417.
[7]	WU C, CHANG J, NI S, et al.The in vitro bioactivity of akermanite ceramics. J. Biomed. Mater. Res. A, 2006, 76: 73-80.
[8]	WU C, CHANG J, WANG J, et al.Preparation and characteristics of a calcium magnesium silicate (Bredigite) bioactive ceramics.Biomaterials, 2005, 26: 2925-2931.
[9]	WU C, CHANG J.Degradation, bioactivity, and cytocompatibility of diopside, akermanite, and bredigite ceramics.J. Biomed. Mater. Res. B, 2007, 83: 53-160.
[10]	WU C, CHANG J, ZHAI W.A novel hardystonite ceramic: preparation and in vitro biocompatibility.Ceram. Int., 2005, 31: 27-31.
[11]	SUCHANEK WL, SHUK P, BYRAPPA K, et al.Mechanochemical- hydrothermal synthesis of carbonated apatite powders at room temperature.Biomaterials, 2002, 23: 699-710.
[12]	KOUTSOPOULOS S.Synthesis and characterization of hydroxyapatite crystals: a review study on the analytical methods.J. Biomed. Mater. Res., 2002, 62: 600-612.
[13]	HENCH LL.Bioceramics: from concept to clinic.J. Am. Ceram. Soc., 1991, 74: 1487-1510.
[14]	VALLET-REGI V, SALINAS A J, ROMAN J, et al.Effect of magnesium content on the in vitro bioactivity of CaO-MgO-SiO2-P2O5 Sol-Gel glasses.J. Mater. Chem., 1999, 9: 515-518.
[15]	PEREZ-PARIENTE J, BALAS F, REGI M V.Surface and chemical study of SiO2-P2O5-CaO(MgO) bioactive glasses.Chem. Mater., 2000, 12: 750-755.
[16]	COSTANTITI L, BOUROPOULOS N, FATOULOS D G, et al.Synthesis of carbon nanotubes loaded hydroxyapatite: potential for controlled drug release of bone implants.J. Adv. Ceram., 2016, 5(3): 232-243.

Spark Plasma Sintering of Bioactive Ca₂MgSi₂O₇ Ceramics

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