Journal of Inorganic Materials ›› 2017, Vol. 32 ›› Issue (1): 107-112.doi: 10.15541/jim20160143

• Orginal Article • Previous Articles    

Sol-Gel-derived Mesoporous Calcium Aluminum Phosphate Bioactive Glasses with High Surface Area

Peng-Fei MA1,2, Ri-Hong LI1(), Long ZHANG1()   

  1. 1. Key Laboratory of Materials for High Power Laser, Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Science, Shanghai 201800, China
    2. University of Chinese Academy of Sciences, Beijing 100039, China
  • Received:2016-03-14 Online:2017-01-20 Published:2016-12-15
  • About author:MA Peng-Fei (1989–), male, candidate of Master degree. Email:
  • Supported by:
    Foundation item: National Natural Science Foundation of China (1308491G00)


High surface area mesoporous bioactive glasses (MBGs) with composition CaO-Al2O3-P2O5 were fabricated using a simple aqueous Sol-Gel method without any template. Structural characterization of the phosphate-based MBGs was performed by BET, DTA, XRD and FTIR, and MBGs’ in vitro bioactivity was evaluated by soaking them in simulate body fluid for up to 15 d at 36.5℃. The highest specific surface area is found to be 461.1 m2/g for the MBG with 5mol% CaO, and it decreased with increasing CaO content. And the glass structure for all the samples was confirmed by XRD and FTIR. However, the MBG with 20mol% CaO exhibits the best in vitro bioactivity using simulated body fluid among all samples. The unique combination of a higher specific surface area and relatively high CaO content enables mesoporous calcium aluminum phosphate bioactive glasses to be promising candidates for biomedical applications.

Key words: mesoporous, phosphate glass, bioactive, Sol-Gel

CLC Number: 

  • TQ174