Effects of Poly(Ethylene Glycol) on Preparation of AmorphousCalcium Phosphate

Abstract

Abstract: A stable amorphous calcium phosphate (ACP) was prepared by a wet chemical method at a low temperature in the presence of poly(ethylene glycol) (PEG). The effects of
PEG:CaCl₂ ratios and the molecule weight of PEG on the stability of ACP in the aqueous solution were investigated. The results show that the optimized preparation conditions
for stable ACP are PEG:CaCl₂ ratio of 1:1 and the PEG molecule weight of 10000. The role of PEG in stabilizing ACP in the aqueous solution is that PEG is easy to exist in the interstices between the ACP Ca₉(PO₄)₆
clusters and adsorbed around ACP particles, and inhibits ACP transformations to crystalline hydroxyapatite.

Key words: amorphous calcium phosphate, poly（ethylene glycol）, biomaterials

CLC Number:

TB383

LI Yan-Bao,WENG Wen-Jian,CHENG Kui,DU Pi-Yi,SHEN Ge,HAN Gao-Rong. Effects of Poly(Ethylene Glycol) on Preparation of AmorphousCalcium Phosphate[J]. Journal of Inorganic Materials.

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Effects of Poly(Ethylene Glycol) on Preparation of AmorphousCalcium Phosphate

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