Preparation and Properties of Mesoporous Bioactive Glass / Demineralized Bone Composite Scaffolds

doi:10.3724/SP.J.1077.2011.01068

Abstract

Abstract: The composite scaffolds (MBG/DB) were prepared successfully through immersing the mesoporous bioactive glass powders into the demineralized bones. The bovine cancellous bone, demineralized bone, composite scaffold were investigated and characterized by FTIR, SEM, XRD and universal electromechanical testing machine. The results show that the compressive strength of the demineralized bones is about (1.10±0.31)MPa, the porosity is about 71% and the pore size is in the range from 200 to 600μm. However, the porosity and the compressive strength of the composite scaffolds are decreased to 40% and increase markedly to (8.49±2.14)MPa, respectively. Meanwhile, the composite scaffolds show good bioactivity in vitro.

Key words: mesoporous bioactive glass, demineralized bone, composite scaffold, bioactivity

CLC Number:

R318

XUE Shi-Zhuang, ZHU Hai-Lin, CHEN Jian-Yong, FENG Xin-Xing, CHANG Jiang. Preparation and Properties of Mesoporous Bioactive Glass / Demineralized Bone Composite Scaffolds[J]. Journal of Inorganic Materials, 2011, 26(10): 1068-1072.

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