Adv. Search
Journal of Inorganic Materials

Journal of Inorganic Materials >

2006 , Vol. 21 >Issue 3: 645 - 650

DOI: https://doi.org/10.3724/SP.J.1077.2006.00645

Research Paper

Fabrication of Transparent β-Ca3(PO4)2 Bioceramics by Spark Plasma Sintering Technique using Ultrafine Powders

  • LIN Kai-Li ,
  • QIN Chao ,
  • NI Si-Yu ,
  • CHEN Li-Dong ,
  • LU Jian-Xi ,
  • CHANG Jiang
Expand
  • Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China

Received date: 2005-06-22

  Revised date: 2005-09-22

  Online published: 2006-05-20

Fold

Abstract

Ultrafine powders of β-tricalcium (β-Ca3(PO4)2, β-TCP) powders (about 100nm in average size) were obtained by the precipitation method. Transparent β-TCP bioceramics were fabricated by using these ultrafine powders and spark plasma sintering technique at 875℃ for 2min under 40MPa and at the heating rate of 150℃/min. No phases other than β-TCP were detected in the sintered samples. The relative density of the prepared β-TCP was over 99.7%. The results of the FESEM show that the transparent bodies have an average grain size of 250nm and seem to be pore-free. The MTT method shows that the proliferation of bone mesenchymal stem cells on transparent β-TCP bioceramics is much better than that on the polystyrene cell culture cluster.

Key words： nano; ultrafine powders; \beta-tricalcium phosphate; spark plasma sintering; transparent bioceramics

Cite this article

LIN Kai-Li , QIN Chao , NI Si-Yu , CHEN Li-Dong , LU Jian-Xi , CHANG Jiang . Fabrication of Transparent β-Ca3(PO4)2 Bioceramics by Spark Plasma Sintering Technique using Ultrafine Powders[J]. Journal of Inorganic Materials, 2006 , 21(3) : 645 -650 . DOI: 10.3724/SP.J.1077.2006.00645

References

1 Hench L L. J. Am. Ceram. Soc., 1991, 74: 1487-1510.
2 Hench L L. J. Am. Ceram. Soc., 1998, 81: 1705-1728.
3 Ioku K, Kawagoe D, Toya H, et al. Trans. Mater. Res. Soc. Jpn., 2002, 27: 447-449.
4 Kotibuki N, Ioku K, Kawagoe D, et al. Biomaterials, 2005, 26: 779-785.
5 Li J, Hermansson L. Interceram., 1990, 39: 13-15.
6 Fang Y, Agrawal D K, Roy D N, et al. Mater. Let., 1995, 23: 147-151.
7 Uematsu K, Takagi M, Honda T, et al. J. Am. Ceram. Soc., 1989, 72: 1476-1478.
8 周艳平, 王岱峰, 奚益明, 等(ZHOU Yan-Ping, et al). 无机材料学报(Journal of Inorganic Materials), 1999, 14 (4): 674-678.
9 Ito H, Yamada H, Yoshida M, et al. J. Appl. Phys. Jpn., 1988, 27: 1371-1373.
10 刘军芳, 傅正义, 王皓(LIU Jun-Fang, et al). 硅酸盐学报(Journal of the Chinese Ceramic Society), 2003, 31: 320-323.
11 Ringe J, Kaps C, Schmitt B, et al. Cell Tissue Res., 2002, 307: 321-327.
12 Mosmann T. J. Immunological Methods, 1983, 65: 55-63.
13 Wang S W, Chen L D, Hirai T. J. Mater. Res., 2000, 15: 982-987.
14 Gao L, Hong J S, Miyamotho, et al. J. Eure. Ceram. Soc., 2000, 20: 2149-2152.
15 Gu Y W, Loh N H, Khor K A, et al. Biomaterials, 2002, 23: 37-43.
16 Gao L, Wang H Z, Hong J S, et al. NanoStructured Materials, 1999, 11: 43-45.
17 Shen Z J, Adolfsson E, Nygren M, et al. Adv. Mater., 2001, 13: 214-216.
18 Lee Y I, Lee J H, Hong S H, et al. Mater. Res. Bull., 2003, 38: 925-930.
19 Greskovich C, Woods K N. Am. Ceram. Soc. Bull., 1973, 52: 473-478.
Options
Outlines

/

〈 〉