Adv. Search
Journal of Inorganic Materials

Journal of Inorganic Materials >

2008 , Vol. 23 >Issue 6: 1241 - 1245

DOI: https://doi.org/10.3724/SP.J.1077.2008.01241

Research Paper

Investigation of HA/chitosan Composite Coatings Prepared by Sol-Gel on Alkali Treated Titanium Surfaces

  • WANG Ying-Bo ,
  • LU Xiong ,
  • FENG Bo ,
  • QU Shu-Xin ,
  • WENG Jie ,
  • CHEN Jian-Min
Expand
  • 1. Key Lab of Advanced Technologies of Materials, Ministry of Education, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China; 2. State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China

Received date: 2008-01-21

  Revised date: 2008-05-24

  Online published: 2008-11-20

Fold

Abstract

Hydroxyapatite/chitosan (HA/CS) composite coatings were prepared on titanium surfaces by hydro-thermal synthesis and Sol-Gel method. The composition, structure, morphology and biocompatibility of composite coatings were characterized. Ti surfaces are convertedinto super-hydrophilic surfaces by alkali treatment, XRD analysis reveals that the coatings are mainly composed of HA and CS and their compositions are determined by TG analysis. SEM observation shows that the coatings with different HA content have different morphologies. Osteoblasts are cultured on the coatings to evaluate their biocompatibility. Alamar Blue assay indicates that cells on the composite coatings has larger proliferation rate than those on pure titanium. Also the ALP activity of the cells on the composite coatings is higher than that on the pure titanium samples. The results demonstrate that as-prepared HA/CS composite coatings have good biocompatibility.

Key words： Sol-Gel; hydroxyapatite; chitosan; composite coatings

Cite this article

WANG Ying-Bo , LU Xiong , FENG Bo , QU Shu-Xin , WENG Jie , CHEN Jian-Min . Investigation of HA/chitosan Composite Coatings Prepared by Sol-Gel on Alkali Treated Titanium Surfaces[J]. Journal of Inorganic Materials, 2008 , 23(6) : 1241 -1245 . DOI: 10.3724/SP.J.1077.2008.01241

References

[1] Wang J H, Wei C W, Liu H C, et al. Journal of Biomedical Materials Research, 2003, 64A (4): 606-615.
[2] Sivakumar M, Manjubala I, Panduranga R K. Carbohydrate Polymers, 2002, 49 (3): 281-288.
[3] Kim S B, Kim Y J, Yonn T L, et al. Biomaterials, 2004, 25 (26): 5715-5723.
[4] Denkbas E B, Kilicay E, Birlikseven C, et al. Reactive & Functional Polmyers, 2002, 50 (3): 225-232.
[5] 杨洪, 傅山岗. 应用化学, 2005, 22 (1): 87-90.
[6] 赵峰, 尹玉姬, 姚康德, 等. 中国修复重建外科杂志, 2002, 16 (2): 130-133.
[7] Sun F, Pang X, Zhitomirsky I. Journal of Materials Processing Technology, 2008, DOI: 10.1016/j. jmatprotec. 2008. 04. 007.
[8] Jin H H, Lee C H, Lee W K. Materials Letters, 2008, 62 (10-11): 1630-1633.
[9] Redepenning J, Venkataraman G, Chen J, et al. Journal of Biomedical Materials Research, 2003, 66A (2): 411-416.
[10] Pang X, Zhitomirsky I. Materials Chemistry & Physics, 2005, 94 (2-3): 245-251.
[11] Wang J, Apeldoorn A, de Groot K. Journal of Biomedical Materials Research, 2006, 76A (3): 503-511.
[12] Lu Xiong, Wang Yingbo, Yang Xiudong, et al. Journal of Biomedical Materials Research, 2008, 84A (2): 523-534.
[13] Klokkevold P R, Vandemark L, Kenney E B, et al. Journal of Periodontology, 1996, 67 (11): 1170-1175.
[14] 倪斌, 侯春林, 贾连顺, 等. 中华骨科杂志, 1995, 9 (9): 607-609.
Options
Outlines

/

〈 〉