采用溶胶凝胶法，原位合成了铜改性的六方介孔硅 (Cu-HMS)无机抗菌材料. XRD、TG-DTA、ESR、UV-Vis、FT-IR、ESEM、EDS及N₂吸附脱附等对材料结构与性能进行了表征；以大肠杆菌、金黄色葡萄球菌、枯草杆菌及芽孢杆菌作供试菌种，考察了材料的抗菌性能. 结果表明，材料粒子呈规则的叶片状，比表面积为553m²/g，平均孔径约3.6nm，铜以离子形式存在于材料的骨架结构中，材料具有良好的介孔结构和热稳定性，有优良的紫外-可见光吸收性能；在抗菌实验中，材料的抗菌效能较好，抗菌性能稳定持久. 材料用量20mg/L，12h即表现出明显的抑菌作用；用量为200mg/L时，24h后可彻底杀灭大肠杆菌、金黄色葡萄球菌及枯草杆菌.

Coppermodified hexagonal mesoporous silica (Cu-HMS) was in situ prepared with sol-gel method. The structure and the performance of Cu-HMS were characterized by XRD, TG-DTA, ESR, UV-Vis, FT-IR, ESEM, EDS and N₂ adsorptiondesorption isotherms. Based on bacteriostasis experiments of E. coil, S. aureus, B. subtilis and G. bacillus, the antibacterial ability of the sample was also investigated. The results show that the particles of Cu-HMS look like regular thallus, the specific surface area is 533m²/g, the average pore size is 3.6nm, and the copper ions are presented in framework of the sample, especially. The sample has favorable mesoporous structure, thermal stability and ultraviolet-visible-light absorption ability. Furthermore, The bacteriostasis experimental results show that Cu-HMS has favourable and steady antibacterial ability. When the dosage of Cu-HMS is 20mg/L, the bacteriostasis ability may be visibly detected in 12h, while the dosage is up to 200mg/L, E. coil, S. aureus and B. subtilis may be killed after 24h.