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2009 , Vol. 24 >Issue 3: 491 - 496

DOI: https://doi.org/10.3724/SP.J.1077.2009.00491

研究论文

NiTi合金上沉积氮化碳薄膜的力学和血液相容性研究

  • 刘 敏 ,
  • 王继刚
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  • 江苏省先进金属材料重点实验室，东南大学 材料科学与工程学院， 南京 211189

收稿日期: 2008-07-21

  修回日期: 2008-10-17

  网络出版日期: 2009-05-20

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Study on Mechanical Properties and Blood Compatibility of Carbon Nitride Film Deposited on NiTi Alloy

  • LIU Min ,
  • WANG Ji-Gang
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  • Jiangsu Key Laboratory of Advanced Metallic Materials, School of Materials Science and Engineering, Southeast University, Nanjing 211189, China

Received date: 2008-07-21

  Revised date: 2008-10-17

  Online published: 2009-05-20

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摘要

采用磁控溅射法在生物医用NiTi合金基体表面制备了Ti/CNx（x≈0.26）梯度薄膜，并制备了Ti/类金刚石(DLC)以及Ti/TiN薄膜进行对比研究. 利用显微硬度计、划痕仪比较分析了上述各薄膜的力学性能，通过表面接触角法研究了薄膜的亲水性. 着重测试并分析了溶血率和血小板粘附行为，进而对薄膜的血液相容性进行评估. 结果表明：Ti/CNx梯度薄膜与NiTi合金基底的结合牢固，结合力达到63.6N. Ti/CNx薄膜硬度为23.01GPa，和Ti/TiN薄膜硬度相当，略高于Ti/DLC薄膜. 溶血率和血小板粘附试验表明，Ti/CNx梯度薄膜能有效改善NiTi合金基底的亲水性和血液相容性，与Ti/TiN和Ti/DLC薄膜相比，Ti/CNx梯度薄膜具有最小的溶血率，仅为1.12％，并且无论在血小板的粘附数量还是在血小板变形程度都最少，因此具有良好的血液相容性.

关键词： 氮化碳薄膜; 力学性能; 血液相容性

本文引用格式

刘 敏 , 王继刚 . NiTi合金上沉积氮化碳薄膜的力学和血液相容性研究[J]. 无机材料学报, 2009 , 24(3) : 491 -496 . DOI: 10.3724/SP.J.1077.2009.00491

Abstract

Ti/CNx (x≈0.26), as well as Ti/DLC (Diamond-Like Carbon) and Ti/TiN gradient films were deposited on NiTi alloy substrates using DC (direct current) magnetron sputtering method. The mechanical properties concerning hardness and cohesion of the above three films were tested by using microhardness tester and scratch tester, respectively. The surface hydrophilicities of the three films were measured using contact angle measurement. The blood compatibilities of the substrate and the films were evaluated by hemolysis test and platelet adhesion test. The results indicate that the cohesion between Ti/CNx film and NiTi alloy substrate is excellent (63.6N). The hardness of the CNx film (23.01GPa) is nearly equal to that of the TiN film, which is somewhat higher than that of the DLC films. The results of surface hydrophilicity test and platelet adhesion test demonstrate that the hydrophilicity and blood compatibility of NiTi alloy are improved effectively by the modification with the Ti/CNx film. In comparison with Ti/TiN and Ti/DLC gradient films, Ti/CNx film has the minimum hemolysis ratio of 1.12%. Among the above gradient films, the Ti/CNx film has the best blood compatibilities, as indicated by the minimum amount of conglutinated platelets and the least deformation.

Key words： carbon nitride film; mechanical properties; blood compatibility

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