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无机材料学报

无机材料学报

• 研究论文 • 上一篇    下一篇

等离子喷涂HA/Ti复合涂层研究 Ⅱ.生物学性能

郑学斌1; 丁传贤1; 王毅2; 朱雅萍2; 任一萍2   

  1. 1. 中国科学院上海硅酸盐研究所, 上海 200050; 2. 上海市伤骨科研究所, 上海 200025
  • 收稿日期:1999-11-10 修回日期:1999-12-03 出版日期:2000-12-20 网络出版日期:2000-12-20

Plasma Sprayed HA/Ti Composite Coatings Ⅱ. Biological properties

ZHENG Xue-Bin1; DING Chuan-Xian1; WANG Yi2; ZHU Ya-Ping2; REN Yi-Ping 2   

  1. 1.Shanghai Institute of Ceramics; Chinese Academy of Sciences; Shanghai 200050; China; 2. Shanghai Institute of Traumatic Orthopedics; Shanghai 200025; China
  • Received:1999-11-10 Revised:1999-12-03 Published:2000-12-20 Online:2000-12-20

PDF (PC)

940

被引次数

62

摘要： 对等离子喷涂 ＨＡ／Ｔｉ复合涂层进行模拟体液和体外细胞试验，以考察涂层的生物学性能，结果指出，涂层经模拟体液浸泡后，表面覆盖一层碳酸磷灰石（ｃａｒｂｏｎａｔｅ－ａｐａｔｉｔｅ），这表明涂层具有良好的生物活性．粗糙的涂层表面易于形成碳酸磷灰石．模拟体液的浓度太小或ＰＨ值太大，均会导致碳酸磷灰石层不能在涂层表面形成．体外细胞试验显示，成骨细胞能在涂层表面紧密贴壁并正常生长，显示涂层具有优良的生物相容性．

关键词: HA涂层, HA/Ti复合涂层, 模拟体液试验, 细胞试验

Abstract: SBF test and cell culture in vitro were carried out to evaluate the biological properties of plasma sprayed HA/Ti composite coatings.
Results obtained show that the coating surfaces will be covered by carbonate-apatite layer after being immersed in SBF for 1 day, which indicate that the composite coatings possess good bioactivity.
Carbonate-apatite layer is inclined to form on the rougher coating surface. Low concentration and high pH value of SBF are harmful to
the formation of carbonate-apatite layer. Excellent biocompatibility of the composite coatings can be confirmed by osteoblasts attaching firmly
and growing well on the coating surface.

Key words: hydroxyapatite coating, HA/Ti composite coating, SBF test, cell culture

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