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图9 NaYF4: Yb/Er@NaGdF4@金属有机框架(MOFs)@阿霉素(DOX)的制备及其UCL/MRI应用[67]

Fig. 9 Preparation and UCL/MRI application of NaYF4: Yb/Er@NaGdF4@metal-organic frameworks (MOFs) @doxorubicin (DOX)[67] (a) Schematic illustration of NaYF4: Yb/Er@NaGdF4@MOFs (UCMOFs) for dual pH-response drug release, UCL imaging and MRI; (b) Confocal fluorescence images of HeLa cells after incubation with NaYF4: Yb/Er@NaGdF4@MOFs@DOX (UCMOFs@D) for 2, 4 and 6 h at 37 ℃, with purple indicating released anticancer drug DOX, green and red indicating UCL (scale bar: 20 µm)