上转换荧光探针辅助的光学成像技术在肿瘤显影中的应用研究进展

海热古·吐逊, 郭乐, 丁嘉仪, 周嘉琪, 张学良, 努尔尼沙·阿力甫

Research Progress of Optical Bioimaging Technology Assisted by Upconversion Fluorescence Probes in Tumor Imaging

HAIREGU Tuxun, GUO Le, DING Jiayi, ZHOU Jiaqi, ZHANG Xueliang, NUERNISHA Alifu

图2 UCNPs的组成、UCL和荧光发射能级图[31-32]

Fig. 2 Composition, upconversion luminescence (UCL) emissions and fluorescent energy-level diagrams of the UCNPs[31-32] (a) Schematic diagram of UCNPs; (b) Typical UCL emissions of Yb3+-Er3+ and Yb3+-Tm3+ co-doped UCNPs under 980 nm excitation[31]; (c) Partial energy-level diagrams of lanthanide ions[32]